参考文献アーカイブ：NOD/ShiJcl

 

日本クレア 関連製品 : NOD/ShiJcl

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1997

• Koyanagi Y, Tanaka Y., Tanaka R., Misawa N., Kawano Y., Tanaka T., Miyasaka M., Ito M., Ueyama Y., Yamamoto N.
  High levels of viremia in hu-PBL-NOD-scid with HIV-1 infection.
  Leukemia. 1997; 11: 109-12. [PMID:9209314]

 

• Koyanagi Y, Tanaka, T., Kira, J., Ito, M., Hioki, K., Misawa, N., Kawano, Y., Yamasaki, K., Tanaka, R., Suzuki, Y., Ueyama, Y., Terada, E., Tanaka, T., Miyasaka, M., Kobayashi, T., Kumazawa, Y. & Yamamoto, N.
  Primary viremia and CNS inavasion with HIV-1 in a novel hu-PBL-immunodeficient mouse.
  J Virol. 1997; 71: 2417-24. [PMID:9032379]

 

1998

• Xu MJ, Tsuji K, Ueda T, Mukouyama YS, Hara T, Yang FC, Ebihara Y, Matsuoka S, Manabe A, Kikuchi A, Ito M, Miyajima A, Nakahata T.
  Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines.
  Blood. 1998; 92(6): 2032-40. [PMID: 9731061]

 

• 植田高弘, 吉野浩, 海老原康博, 真部淳, 菊地陽, 辻浩一郎, 中畑龍俊.
  NOD-SCIDマウスを用いたヒトさい帯血造血幹細胞の造血再構築能の検討.
  日本産婦人科･新生児血液学会誌. 1998; 8(2): 57-8.

 

• 蔵本悦郎, 徳永徹, 山本三郎, 本多三男.
  宿主媒介性抗エイズウイルス薬としてのオリゴヌクレオチドの探索研究 (ヒューマンサイエンス振興財団S).
  エイズ医薬品等開発研究報告 平成9年度. 1998; 19-26.

 

1999

• 中畑龍俊.
  造血幹細胞のex vivo増幅と臨床応用に関する研究 (厚生省S). 造血細胞移植と免疫応答に関する研究班報告書 平成10年度 造血細胞移植の円滑な実施と成績向上に必要な基盤の整備に関する研究
  厚生科学研究費補助金免疫･アレルギー等研究事業(臓器移植部門). 1999; 171-9.

 

• 田中勇悦.
  SCID/huマウスによる感染病態の解析 (文部省S).
  エイズの病態と制御に関する基礎研究 平成7-9年度. 1999; 301-6.

 

• 中畑龍俊.
  造血幹細胞のex vivo増幅と臨床応用に関する研究 (厚生省S).
  免疫･アレルギー等研究事業(臓器移植部門)研究報告書 平成10年度. 1999; 205-13.

 

2000

• Ueda T, Tsuji K, Yoshino H, Ebihara Y, Yagasaki H, Hisakawa H, Mitsui T, Manabe A, Tanaka R, Kobayashi K, Ito M, Yasukawa K, Nakahata T.
  Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor.
  J Clin Invest. 2000; 105: 1013-21. [PMID:10749580]

 

• Ueda T, Yoshino H, Kobayashi K, Kawahata M, Ebihara Y, Ito M, Asano S, Nakahata T, Tsuji K.
  Hematopoietic repopulating ability of cord blood CD34(+) cells in NOD/Shi-scid mice.
  Stem Cells. 2000; 18: 204-13. [PMID:10840074]

 

• Yoshino H, Ueda T, Kawahata M, Kobayashi K, Ebihara Y, Manabe A, Tanaka R, Ito M, Asano S, Nakahata T, Tsuji K.
  Natural killer cell depletion by anti-asialo GM1 antiserum treatment enhances human hematopoietic stem cell engraftment in NOD/Shi-scid mice.
  Bone Marrow Transplant. 2000; 26: 1211-6. [PMID: 11149733]

 

• Saito-Ito A, Tsuji M, Wei Q, He S, Matsui T, Kohsaki M, Arai S, Kamiyama T, Hioki K, Ishihara C.
  Transfusion-acquired, autochthonous human babesiosis in Japan: isolation of Babesia microti-like parasites with hu-RBC-SCID mice.
  J Clin Microbiol. 2000; 38(12): 4511-6. [PMID: 11101588]

 

2001

• Ma F, Wada M, Yoshino H, Ebihara Y, Ishii T, Manabe A, Tanaka R, Maekawa T, Ito M, Mugishima H, Asano S, akahata T, Tsuji K.
  Development of human lymphohematopoietic stem and progenitor cells defined by expression of CD34 and CD81.
  Blood. 2001; 97: 3755-62. [PMID: 11389013]

 

• Ueda T, Yoshida M, Yoshino H, Kobayashi K, M. K, Ebihara Y, Ito M, Asano S, Nakahata T, Tsuji K.
  Hematopoietic Capability of CD34+ Cord Blood Cells. A Comparison With CD34+ Adult Bone Marrow Cells.
  Int J Hematol. 2001;73:457-62. [PMID: 11503959]

 

• Kosugi H, Ito M, Yamamoto Y, Towatari M, Ito M, Ueda R, Saito H, Naoe T.
  In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice.
  Jpn J Cancer Res. 2001; 92(5): 529-36. [PMID: 11376562]

 

2002

• Li C, Ando K, Kametani Y, Oki M, Hagihara M, Shimamura K, Habu S, Kato S, Hotta T.
  Reconstitution of functional human B lymphocytes in NOD/SCID mice engrafted with ex vivo expanded CD34(+) cord blood cells.
  Exp Hematol. 2002; 30(9): 1036-43. [PMID: 12225795]

 

2003

• Ishihara C, Zamoto A, Tsuji M, Wei Q, Azuma I, Hioki K.
  Erythrocyte-replaced mouse model for Haemoparasite studies: comparison of NOD/shi-scid and C.B-17/Jcl-scid mouse upon acceptability of human erythrocytes.
  J Vet Med Sci. 2003; 65(8): 831-7. [PMID: 12951413]

 

• 平松英文, 中畑龍俊.
  異種動物を用いたヒト造血幹細胞の測定.
  ファルマシア. 2003; 39(2): 118-122.

 

• 平松英文, 中畑龍俊.
  NOD/SCID/γcnullマウス.
  血液･腫よう科. 2003; 47(1): 46-51.

 

2004

• Zamoto A, Tsuji M, Kawabuchi T, Wei Q, Asakawa M, Ishihara C.
  U.S.-type Babesia microti isolated from small wild mammals in Eastern Hokkaido, Japan.
  J Vet Med Sci. 2004; 66(8): 919-26. [PMID: 15353841]

 

• Andreassen J, Ito A, Ito M, Nakao M, Nakaya K.
  Hymenolepis microstoma: direct life cycle in immunodeficient mice.
  J Helminthol. 2004; 78(1): 1-5. [PMID: 14972030]

 

• Nishishita T, Ouchi K, Zhang X, Inoue M, Inazawa T, Yoshiura K, Kuwabara K, Nakaoka T, Watanabe N, Igura K, Takahashi TA, Yamashita N.
  A potential pro-angiogenic cell therapy with human placenta-derived mesenchymal cells.
  Biochem Biophys Res Commun. 2004; 325(1): 24-31. [PMID: 15522196]

 

2005

• Hidefumi Hiramatsu, Hisanori Fujino, Toshio Heike, Mamoru Ito and Tatsutoshi Nakahata.
  Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice.
  Acta Medica Nagasakiensia. 2005; 50: 39-3.

 

• Kawabuchi T, Tsuji M, Kuwahara S, Nishida A, Shimofurutachi T, Oka H, Ishihara C.
  Isolation of a human erythrocyte-adapted substrain of Babesia rodhaini and analysis of the merozoite surface protein gene sequences.
  J Vet Med Sci. 2005; 67(9): 901-7. [PMID: 16210802]

 

• Yasutake M, Zheng Y, Inoue-Nagamura T, Akagawa E, Tokushima Y, Terashima S, Takahashi TA.
  SCID-repopulating activity of human umbilical cord blood-derived hematopoietic stem and/or progenitor cells in a nonobese diabetic/Shi-SCID mice serial xenotransplantation model and immune cell activities in vitro: a comparative study of the filter method and the hydroxyethyl starch method.
  Transfusion. 2005; 45(12): 1899-908. [PMID: 16371042]

 

2006

• Ishijima T, Kobayashi Y, Lee DS, Ueta YY, Matsui M, Lee JY, Suwa Y, Miyahara K, Suzuki H.
  Cryopreservation of canine ovaries by vitrification.
  J Reprod Dev. 2006; 52(2): 293-9. [PMID: 16394621]

 

• Nakaya K, Mamuti W, Xiao N, Sato MO, Wandra T, Nakao M, Sako Y, Yamasaki H, Ishikawa Y, Craig PS, Schantz PM, Ito A.
  Usefulness of severe combined immunodeficiency (scid) and inbred mice for studies of cysticercosis and echinococcosis.
  Parasitol Int. 2006; 55 Suppl: S91-7. [PMID: 16338168]

 

• Nakamura T, Miyakawa Y, Miyamura A, Yamane A, Suzuki H, Ito M, Ohnishi Y, Ishiwata N, Ikeda Y, Tsuruzoe N.
  A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis.
  Blood. 2006; 107(11): 4300-7. [PMID: 16484588]

 

2007

• Yokota A, Kimura S, Masuda S, Ashihara E, Kuroda J, Sato K, Kamitsuji Y, Kawata E, Deguchi Y, Urasaki Y, Terui Y, Ruthardt M, Ueda T, Hatake K, Inui K, Maekawa T.
  INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity.
  Blood. 2007 Jan 1;109(1):306-14. [PMID: 16954504]

 

• Ohdan H, Zhou W, Tanaka Y, Irei T, Fuchimoto Y, Egawa H, Asahara T.
  Evidence of immune tolerance to blood group antigens in a case of ABO-incompatible pediatric liver transplantation.
  Am J Transplant. 2007 Sep;7(9):2190-4. [PMID: 17640317]

 

• Tomita A, Hiraga J, Kiyoi H, Ninomiya M, Sugimoto T, Ito M, Kinoshita T, Naoe T.
  Epigenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy.
  Int J Hematol. 2007 Jul;86(1):49-57. [PMID: 17675267]

 

• Kimura T, Asada R, Wang J, Kimura T, Morioka M, Matsui K, Kobayashi K, Henmi K, Imai S, Kita M, Tsuji T, Sasaki Y, Ikehara S, Sonoda Y.
  Identification of long-term repopulating potential of human cord blood-derived CD34-flt3- severe combined immunodeficiency-repopulating cells by intra-bone marrow injection.
  Stem Cells. 2007 Jun;25(6):1348-55. [PMID: 17303816]

 

• Yonou H, Ochiai A, Ashimine S, Maeda H, Horiguchi Y, Yoshioka K, Ogawa Y, Hatano T, Tachibana M.
  The bisphosphonate YM529 inhibits osteoblastic bone tumor proliferation of prostate cancer.
  Prostate. 2007 Jun 15;67(9):999-1009. [PMID: 17440967]

 

• Tawara T, Hasegawa K, Sugiura Y, Tahara T, Ishida I, Kataoka S.
  Fully human antibody exhibits pan-human leukocyte antigen-DR recognition and high in vitro/vivo efficacy against human leukocyte antigen-DR-positive lymphomas.
  Cancer Sci. 2007 Jun;98(6):921-8. [PMID: 17428256]

 

2008

• Eguchi H, Kuroiwa Y, Matsui A, Sada M, Nagaya N, Kawano S.
  Intra-bone marrow cotransplantation of donor mesenchymal stem cells in pig-to-NOD/SCID mouse bone marrow transplantation facilitates short-term xenogeneic hematopoietic engraftment.
  Transplant Proc. 2008 Mar;40(2):574-7. [PMID: 18374132]

 

• Suzuki H, Ishijima T, Maruyama S, Yanagimoto Ueta Y, Abe Y, Saitoh H.
  Beneficial effect of desialylated erythropoietin administration on the frozen-thawed canine ovarian xenotransplantation.
  J Assist Reprod Genet. 2008 Nov-Dec;25(11-12):571-5. [PMID: 18972200]

 

• Takeda T, Tezuka Y, Horiuchi M, Hosono K, Iida K, Hatakeyama D, Miyaki S, Kunisada T, Shibata T, Tezuka K.
  Characterization of dental pulp stem cells of human tooth germs.
  J Dent Res. 2008 Jul;87(7):676-81. [PMID: 18573990]

 

• Motohashi N, Uezumi A, Yada E, Fukada S, Fukushima K, Imaizumi K, Miyagoe-Suzuki Y, Takeda S.
  Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts.
  Am J Pathol. 2008 Sep;173(3):781-91. [PMID: 18669618]

 

• Kumano M, Miyake H, Kurahashi T, Yamanaka K, Fujisawa M.
  Enhanced progression of human prostate cancer PC3 cells induced by the microenvironment of the seminal vesicle.
  Br J Cancer. 2008 Jan 29;98(2):356-62. [PMID: 18182987]

 

• Hiroyama T, Sudo K, Aoki N, Miharada K, Danjo I, Fujioka T, Nagasawa T, Nakamura Y.
  Human umbilical cord-derived cells can often serve as feeder cells to maintain primate embryonic stem cells in a state capable of producing hematopoietic cells.
  Cell Biol Int. 2008 Jan;32(1):1-7. [PMID: 17890111]

 

• Hiroyama T, Miharada K, Sudo K, Danjo I, Aoki N, Nakamura Y.
  Establishment of mouse embryonic stem cell-derived erythroid progenitor cell lines able to produce functional red blood cells.
  PLoS One. 2008 Feb 6;3(2):e1544. [PMID: 18253492]

 

• Sangai T, Fujimoto H, Miyamoto S, Maeda H, Nakamura M, Ishii G, Nagai K, Nagashima T, Miyazaki M, Ochiai A.
  Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice.
  Clin Exp Metastasis. 2008;25(4):401-10. [PMID: 18307047]

 

• Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, Sato T, Takimoto R, Niitsu Y, Kato J.
  Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells.
  Exp Hematol. 2008 Sep;36(9):1121-31. [PMID: 18562079]

 

• Hiyama K, Tanimoto K, Nishimura Y, Tsugane M, Fukuba I, Sotomaru Y, Hiyama E, Nishiyama M.
  Exploration of the genes responsible for unlimited proliferation of immortalized lung fibroblasts.
  Exp Lung Res. 2008 Sep;34(7):373-90. [PMID: 18716925]

 

2009

• Ohno N, Kajiume T, Sera Y, Sato T, Kobayashi M.
  Short-term culture of umbilical cord blood-derived CD34 cells enhances engraftment into NOD/SCID mice through increased CXCR4 expression.
  Stem Cells Dev. 2009 Oct;18(8):1221-6. [PMID: 19113880]

 

• Kanazawa Y, Shimada A, Oikawa Y, Okubo Y, Tada A, Imai T, Miyazaki J, Itoh H.
  Induction of anti-whole GAD65 reactivity in vivo results in disease suppression in type 1 diabetes.
  J Autoimmun. 2009 Mar;32(2):104-9. [PMID: 19188044]

 

• Okura H, Komoda H, Saga A, Kakuta-Yamamoto A, Hamada Y, Fumimoto Y, Lee CM, Ichinose A, Sawa Y, Matsuyama A.
  Properties of hepatocyte-like cell clusters from human adipose tissue-derived mesenchymal stem cells.
  Tissue Eng Part C Methods. 2010 Aug;16(4):761-70. [PMID: 19839740]

 

• Matsubara K, Uchida N, Matsubara Y, Hyodo S, Ito M.
  Detection of fetal cells in the maternal kidney during gestation in the mouse.
  Tohoku J Exp Med. 2009 Jun;218(2):107-13. [PMID: 19478466]

 

2010

• Ishii T, Yasuchika K, Suemori H, Nakatsuji N, Ikai I, Uemoto S.
  Alpha-fetoprotein producing cells act as cancer progenitor cells in human cholangiocarcinoma.
  Cancer Lett. 2010 Aug 1;294(1):25-34. [PMID: 20149523]

 

• Kishi M, Yasuda H, Abe Y, Sasaki H, Shimizu M, Arai T, Okumachi Y, Moriyama H, Hara K, Yokono K, Nagata M.
  Regulatory CD8+ T cells induced by exposure to all-trans retinoic acid and TGF-beta suppress autoimmune diabetes.
  Biochem Biophys Res Commun. 2010 Mar 26;394(1):228-32. [PMID: 20206130]

 

• Fukaya R, Ohta S, Yamaguchi M, Fujii H, Kawakami Y, Kawase T, Toda M.
  Isolation of cancer stem-like cells from a side population of a human glioblastoma cell line, SK-MG-1.
  Cancer Lett. 2010 May 28;291(2):150-7. [PMID: 19913993]

 

• Takeda H, Fujimori Y, Kai S, Ogawa H, Nakano T.
  CD318/CUB-domain-containing protein 1 expression on cord blood hematopoietic progenitors.
  Exp Ther Med. 2010 May;1(3):497-501. [PMID: 22993567]

 

• Mihara K, Yanagihara K, Takigahira M, Kitanaka A, Imai C, Bhattacharyya J, Kubo T, Takei Y, Yasunaga S, Takihara Y, Kimura A.
  Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma.
  Br J Haematol. 2010 Oct;151(1):37-46. [PMID: 20678160]

 

• Okura H, Komoda H, Saga A, Kakuta-Yamamoto A, Hamada Y, Fumimoto Y, Lee CM, Ichinose A, Sawa Y, Matsuyama A.
  Properties of hepatocyte-like cell clusters from human adipose tissue-derived mesenchymal stem cells.
  Tissue Eng Part C Methods. 2010;16(4):761-70. [PMID: 19839740]

 

2011

• Wada H, Kojo S, Kusama C, Okamoto N, Sato Y, Ishizuka B, Seino K.
  Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.
  Int Immunol. 2011 Jan;23(1):65-74. [PMID: 21135032]

 

• Sasaki N, Ishii T, Kamimura R, Kajiwara M, Machimoto T, Nakatsuji N, Suemori H, Ikai I, Yasuchika K, Uemoto S.
  Alpha-fetoprotein-producing pancreatic cancer cells possess cancer stem cell characteristics.
  Cancer Lett. 2011 Sep 28;308(2):152-61. [PMID: 21616586]

 

• Yao H, Ashihara E, Strovel JW, Nakagawa Y, Kuroda J, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hayashi Y, Shimazaki C, Taniwaki M, Strand K, Padia J, Hirai H, Kimura S, Maekawa T.
  AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model.
  Blood Cancer J. 2011 Nov;1(11):e43. [PMID: 22829079]

 

• Yamaoka E, Hiyama E, Sotomaru Y, Onitake Y, Fukuba I, Sudo T, Sueda T, Hiyama K.
  Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells.
  Int J Oncol. 2011 Jul;39(1):5-11. [PMID: 21573488]

 

• Abdel-Ghani MA, Abe Y, Asano T, Suzuki H.
  Effect of graft site and gonadotrophin treatment on follicular development of canine ovarian grafts transplanted to NOD-SCID mice.
  Reprod Med Biol. 2011 May 28;10(4):259-266. [PMID: 29699099]

 

• Wang B, Miyagoe-Suzuki Y, Yada E, Ito N, Nishiyama T, Nakamura M, Ono Y, Motohashi N, Segawa M, Masuda S, Takeda S.
  Reprogramming efficiency and quality of induced Pluripotent Stem Cells (iPSCs) generated from muscle-derived fibroblasts of mdx mice at different ages.
  PLoS Curr. 2011 Oct 27;3:RRN1274. [PMID: 22101343]

 

• Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A.
  Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase.
  PLoS One. 2011;6(9):e24298. [PMID: 21931675]

 

• Okazaki T, Okazaki IM, Wang J, Sugiura D, Nakaki F, Yoshida T, Kato Y, Fagarasan S, Muramatsu M, Eto T, Hioki K, Honjo T.
  PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice.
  J Exp Med. 2011 Feb 14;208(2):395-407. [PMID: 21300912]

 

• Abe M, Suzuki K, Sakata C, Sugasawa K, Hirayama F, Koga Y, Kawasaki T, Naganuma S, Itoh H.
  Pharmacological profile of AS1670542, a novel orally-active human thrombopoietin receptor agonist.
  Eur J Pharmacol. 2011 Jan 10;650(1):58-63. [PMID: 20950606]

 

• Kikuchi T, Morizane A, Doi D, Onoe H, Hayashi T, Kawasaki T, Saiki H, Miyamoto S, Takahashi J.
  Survival of human induced pluripotent stem cell-derived midbrain dopaminergic neurons in the brain of a primate model of Parkinson's disease.
  J Parkinsons Dis. 2011;1(4):395-412. [PMID: 23933658]

 

• Yamauchi C, Fujii S, Kimura T, Kuwata T, Wada N, Mukai H, Matsumoto N, Fukayama M, Ochiai A.
  E-cadherin expression on human carcinoma cell affects trastuzumab-mediated antibody-dependent cellular cytotoxicity through killer cell lectin-like receptor G1 on natural killer cells.
  Int J Cancer. 2011 May 1;128(9):2125-37. [PMID: 21387286]

 

• Matsuura Y, Yagi H, Matsuda S, Itano O, Aiura K, Kuroda S, Ueda M, Kitagawa Y.
  Human liver-specific nanocarrier in a novel mouse xenograft model bearing noncancerous human liver tissue.
  Eur Surg Res. 2011;46(2):65-72. [PMID: 21178358]

 

• Kawamoto E, Sasaki H, Okiyama E, Kanai T, Ueshiba H, Ohnishi N, Sawada T, Hayashimoto N, Takakura A, Itoh T.
  Pathogenicity of Pasteurella pneumotropica in Immunodeficient NOD/ShiJic-scid/Jcl and Immunocompetent Crlj:CD1 (ICR) Mice.
  Exp Anim. 2011;60(5):463-70. [PMID: 22041283]

 

2012

• Kimura S, Kuramoto K, Homan J, Naruoka H, Ego T, Nogawa M, Sugahara S, Naito H.
  Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1.
  Anticancer Res. 2012 Mar;32(3):795-8. [PMID: 22399596]

 

• Hosen N, Ichihara H, Mugitani A, Aoyama Y, Fukuda Y, Kishida S, Matsuoka Y, Nakajima H, Kawakami M, Yamagami T, Fuji S, Tamaki H, Nakao T, Sugiyama H, Nishida S, Tsuboi A, Iida S, Hino M, Oka Y, Oji Y.
  CD48 as a novel molecular target for antibody therapy in multiple myeloma.
  Br J Haematol. 2012 Jan;156(2):213-24. [PMID: 22098460]

 

• Matsumoto K, Yokoo T, Matsunari H, Iwai S, Yokote S, Teratani T, Gheisari Y, Tsuji O, Okano H, Utsunomiya Y, Hosoya T, Okano HJ, Nagashima H, Kobayashi E.
  Xenotransplanted embryonic kidney provides a niche for endogenous mesenchymal stem cell differentiation into erythropoietin-producing tissue.
  Stem Cells. 2012 Jun;30(6):1228-35. [PMID: 22488594]

 

• Hayashi T, Ding Q, Kuwahata T, Maeda K, Miyazaki Y, Matsubara S, Obara T, Natsugoe S, Takao S.
  Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine.
  Cancer Sci. 2012 May;103(5):889-96. [PMID: 22320450]

 

• Matsushima-Miyagi T, Hatano K, Nomura M, Li-Wen L, Nishikawa T, Saga K, Shimbo T, Kaneda Y.
  TRAIL and Noxa are selectively upregulated in prostate cancer cells downstream of the RIG-I/MAVS signaling pathway by nonreplicating Sendai virus particles.
  Clin Cancer Res. 2012 Nov 15;18(22):6271-83. [PMID: 23014529]

 

2013

• Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N.
  Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.
  Diabetologia. 2013 Aug;56(8):1773-80. [PMID: 23699989]

 

• Suzuki N, Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M, Nakauchi H.
  Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.
  Mol Ther. 2013 Jul;21(7):1424-31. [PMID: 23670574]

 

• Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI.
  Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration.
  Biomaterials. 2013 Jul;34(22):5581-7. [PMID: 23623324]

 

• Hoshina D, Abe R, Yoshioka N, Saito N, Hata H, Fujita Y, Aoyagi S, Shimizu H.
  Establishment of a novel experimental model of human angiosarcoma and a VEGF-targeting therapeutic experiment.
  J Dermatol Sci. 2013 May;70(2):116-22. [PMID: 23522954]

 

• Kobayashi M, Kaneko-Koike C, Abiru N, Uchida T, Akazawa S, Nakamura K, Kuriya G, Satoh T, Ida H, Kawasaki E, Yamasaki H, Nagayama Y, Sasaki H, Kawakami A.
  Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice.
  Clin Exp Immunol. 2013 Sep;173(3):411-8. [PMID: 23663075]

 

• Okuyama H, Yoshida T, Endo H, Nakayama M, Nonomura N, Nishimura K, Inoue M.
  Involvement of heregulin/HER3 in the primary culture of human urothelial cancer.
  J Urol. 2013 Jul;190(1):302-10. [PMID: 23313199]

 

• Chiba Y, Mizoguchi I, Mitobe K, Higuchi K, Nagai H, Nishigori C, Mizuguchi J, Yoshimoto T.
  IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner.
  PLoS One. 2013 Oct 14;8(10):e76159. [PMID: 24155891]

 

• Chen MH, Soda Y, Izawa K, Kobayashi S, Tani K, Maruyama K, Tojo A, Asano S.
  A versatile drug delivery system using streptavidin-tagged pegylated liposomes and biotinylated biomaterials.
  Int J Pharm. 2013 Sep 15;454(1):478-85. [PMID: 23806815]

 

• Takahashi RU, Takeshita F, Honma K, Ono M, Kato K, Ochiya T.
  Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3β.
  Sci Rep. 2013;3:2474. [PMID: 23959174]

 

• Yamamoto M, Taguchi Y, Ito-Kureha T, Semba K, Yamaguchi N, Inoue J.
  NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype.
  Nat Commun. 2013;4:2299. [PMID: 23934482

 

• Hatano K, Yamaguchi S, Nimura K, Murakami K, Nagahara A, Fujita K, Uemura M, Nakai Y, Tsuchiya M, Nakayama M, Nonomura N, Kaneda Y.
  Residual prostate cancer cells after docetaxel therapy increase the tumorigenic potential via constitutive signaling of CXCR4, ERK1/2 and c-Myc.
  Mol Cancer Res. 2013 Sep;11(9):1088-100. [PMID: 23788635]

 

• Makino Y, Yamaza H, Akiyama K, Ma L, Hoshino Y, Nonaka K, Terada Y, Kukita T, Shi S, Yamaza T.
  Immune therapeutic potential of stem cells from human supernumerary teeth.
  J Dent Res. 2013 Jul;92(7):609-15. [PMID: 23697344]

 

2014

• Sogabe S, Togashi Y, Kato H, Kogita A, Mizukami T, Sakamoto Y, Banno E, Terashima M, Hayashi H, de Velasco MA, Sakai K, Fujita Y, Tomida S, Yasuda T, Takeyama Y, Okuno K, Nishio K.
  MEK inhibitor for gastric cancer with MEK1 gene mutations.
  Mol Cancer Ther. 2014 Dec;13(12):3098-106. [PMID: 25253779]

 

• Yasuno T, Osafune K, Sakurai H, Asaka I, Tanaka A, Yamaguchi S, Yamada K, Hitomi H, Arai S, Kurose Y, Higaki Y, Sudo M, Ando S, Nakashima H, Saito T, Kaneoka H.
  Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency.
  Biochem Biophys Res Commun. 2014 May 30;448(2):175-81. [PMID: 24780397]

 

• Takebayashi K, Murata S, Yamamoto H, Ishida M, Yamaguchi T, Kojima M, Shimizu T, Shiomi H, Sonoda H, Naka S, Mekata E, Okabe H, Tani T.
  Surgery-induced peritoneal cancer cells in patients who have undergone curative gastrectomy for gastric cancer.
  Ann Surg Oncol. 2014 Jun;21(6):1991-7. [PMID: 24499832]

 

• Fukamachi K, Iigo M, Hagiwara Y, Shibata K, Futakuchi M, Alexander DB, Hino O, Suzui M, Tsuda H.
  Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer.
  PLoS One. 2014 Oct 27;9(10):e111481. [PMID: 25347530]

 

• Ozawa M, Kawakami E, Sakamoto R, Shibasaki T, Goto A, Yoshida N.
  Development of FGF2-dependent pluripotent stem cells showing naive state characteristics from murine preimplantation inner cell mass.
  Stem Cell Res. 2014 Jul;13(1):75-87. [PMID: 24835670]

 

• Nobutani K, Shimono Y, Yoshida M, Mizutani K, Minami A, Kono S, Mukohara T, Yamasaki T, Itoh T, Takao S, Minami H, Azuma T, Takai Y.
  Absence of primary cilia in cell cycle-arrested human breast cancer cells.
  Genes Cells. 2014 Feb;19(2):141-52. [PMID: 24330390]

 

• Fujiwara T, Katsuda T, Hagiwara K, Kosaka N, Yoshioka Y, Takahashi RU, Takeshita F, Kubota D, Kondo T, Ichikawa H, Yoshida A, Kobayashi E, Kawai A, Ozaki T, Ochiya T.
  Clinical relevance and therapeutic significance of microRNA-133a expression profiles and functions in malignant osteosarcoma-initiating cells.
  Stem Cells. 2014 Apr;32(4):959-73. [PMID: 24715690]

 

2015

• Saito T, Yano F, Mori D, Kawata M, Hoshi K, Takato T, Masaki H, Otsu M, Eto K, Nakauchi H, Chung UI, Tanaka S.
  Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells.
  Biomed Res. 2015;36(3):179-86. [PMID: 26106047]

 

• Yokoo M, Kubota Y, Tabe Y, Kimura S.
  Comparative study of the anti-leukemic effects of imatinib mesylate, Glivec™ tablet and its generic formulation, OHK9511.
  Biol Pharm Bull. 2015;38(3):411-6. [PMID: 25757922]

 

• Nobutani K, Shimono Y, Mizutani K, Ueda Y, Suzuki T, Kitayama M, Minami A, Momose K, Miyawaki K, Akashi K, Azuma T, Takai Y.
  Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy.
  PLoS One. 2015 Jun 17;10(6):e0130032. [PMID: 26083776]

 

• Yamashita D, Kondo T, Ohue S, Takahashi H, Ishikawa M, Matoba R, Suehiro S, Kohno S, Harada H, Tanaka J, Ohnishi T.
  miR340 suppresses the stem-like cell function of glioma-initiating cells by targeting tissue plasminogen activator.
  Cancer Res. 2015 Mar 15;75(6):1123-33. [PMID: 25627976]

 

• Yata K, Beder LB, Tamagawa S, Hotomi M, Hirohashi Y, Grenman R, Yamanaka N.
  MicroRNA expression profiles of cancer stem cells in head and neck squamous cell carcinoma.
  Int J Oncol. 2015 Oct;47(4):1249-56. [PMID: 26323893]

 

• Akazawa S, Kobayashi M, Kuriya G, Horie I, Yu L, Yamasaki H, Okita M, Nagayama Y, Matsuyama T, Akbari M, Yui K, Kawakami A, Abiru N.
  Haploinsufficiency of interferon regulatory factor 4 strongly protects against autoimmune diabetes in NOD mice.
  Diabetologia. 2015 Nov;58(11):2606-14. [PMID: 26271342]

 

• Nishikawa S, Konno M, Hamabe A, Hasegawa S, Kano Y, Fukusumi T, Satoh T, Takiguchi S, Mori M, Doki Y, Ishii H.
  Surgically resected human tumors reveal the biological significance of the gastric cancer stem cell markers CD44 and CD26.
  Oncol Lett. 2015 May;9(5):2361-2367. [PMID: 26137071]

 

• Huynh LM, Shinagawa T, Ishii S.
  Two Histone Variants TH2A and TH2B Enhance Human Induced Pluripotent Stem Cell Generation.
  Stem Cells Dev. 2016 Feb 1;25(3):251-8. [PMID: 26649967]

 

• Yokoo M, Kubota Y, Motoyama K, Higashi T, Taniyoshi M, Tokumaru H, Nishiyama R, Tabe Y, Mochinaga S, Sato A, Sueoka-Aragane N, Sueoka E, Arima H, Irie T, Kimura S.
  2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent.
  PLoS One. 2015 Nov 4;10(11):e0141946. [PMID: 26535909]

 

• Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A.
  Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia.
  Sci Adv. 2015 Apr 24;1(3):e1400203. [PMID: 26601161]

 

• Toriumi T, Takayama N, Murakami M, Sato M, Yuguchi M, Yamazaki Y, Eto K, Otsu M, Nakauchi H, Shirakawa T, Isokawa K, Honda MJ.
  Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth.
  Biomed Res. 2015;36(1):31-45. [PMID: 25749149]

 

• Kambayashi S, Igase M, Kobayashi K, Kimura A, Shimokawa Miyama T, Baba K, Noguchi S, Mizuno T, Okuda M.
  Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma.
  J Vet Med Sci. 2015 Nov;77(11):1405-12. [PMID: 26050843]

 

• Itakura G, Kobayashi Y, Nishimura S, Iwai H, Takano M, Iwanami A, Toyama Y, Okano H, Nakamura M.
  Control of the Survival and Growth of Human Glioblastoma Grafted Into the Spinal Cord of Mice by Taking Advantage of Immunorejection.
  Cell Transplant. 2015;24(7):1299-311. [PMID: 24818989]

 

• Itaba N, Matsumi Y, Okinaka K, Ashla AA, Kono Y, Osaki M, Morimoto M, Sugiyama N, Ohashi K, Okano T, Shiota G.
  Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice.
  Sci Rep. 2015 Nov 10;5:16169. [PMID: 26553591]

 

2016

• Yoshiyama A, Morii T, Ohtsuka K, Ohnishi H, Tajima T, Aoyagi T, Mochizuki K, Satomi K, Ichimura S.
  Development of Stemness in Cancer Cell Lines Resistant to the Anticancer Effects of Zoledronic Acid.
  Anticancer Res. 2016 Feb;36(2):625-31. [PMID: 26851017]

 

• Munakata K, Uemura M, Tanaka S, Kawai K, Kitahara T, Miyo M, Kano Y, Nishikawa S, Fukusumi T, Takahashi Y, Hata T, Nishimura J, Takemasa I, Mizushima T, Ikenaga M, Kato T, Murata K, Carethers JM, Yamamoto H, Doki Y, Mori M.
  Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity.
  Clin Cancer Res. 2016 Nov 1;22(21):5277-5286. [PMID: 27166395]

 

• Chen F, Ishikawa Y, Akashi A, Naoe T, Kiyoi H.
  Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells.
  Oncotarget. 2016 Jul 26;7(30):47018-47032. [PMID: 27331411]

 

• Imai Y, Ohta E, Takeda S, Sunamura S, Ishibashi M, Tamura H, Wang YH, Deguchi A, Tanaka J, Maru Y, Motoji T.
  Histone deacetylase inhibitor panobinostat induces calcineurin degradation in multiple myeloma.
  JCI Insight. 2016 Apr 21;1(5):e85061. [PMID: 27699258]

 

• Fujinaga H, Watanabe N, Kato T, Tamano M, Terao M, Takada S, Ito Y, Umezawa A, Kuroda M.
  Cord blood-derived endothelial colony-forming cell function is disrupted in congenital diaphragmatic hernia.
  Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1143-54. [PMID: 27130531]

 

2017

• Abe T, Matsuoka Y, Nagao Y, Sonoda Y, Hanazono Y.
  CD34-negative hematopoietic stem cells show distinct expression profiles of homing molecules that limit engraftment in mice and sheep.
  Int J Hematol. 2017 Nov;106(5):631-637. [PMID: 28687990]

 

• Sasai K, Takao-Rikitsu E, Sukezane T, Yanagita E, Nakagawa H, Itoh-Yagi M, Izumi Y, Itoh T, Akagi T.
  Engineering cancer stem-like cells from normal human lung epithelial cells.
  PLoS One. 2017 Apr 5;12(4):e0175147. [PMID: 28380052]

 

• Kondo Y, Toyoda T, Ito R, Funato M, Hosokawa Y, Matsui S, Sudo T, Nakamura M, Okada C, Zhuang X, Watanabe A, Ohta A, Inagaki N, Osafune K.
  Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells.
  Diabetologia. 2017 Aug;60(8):1454-1466. [PMID: 28534195]

 

• Liu S, Hasegawa H, Takemasa E, Suzuki Y, Oka K, Kiyoi T, Takeda H, Ogasawara T, Sawasaki T, Yasukawa M, Maeyama K.
  Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models.
  J Immunol. 2017 Sep 1;199(5):1584-1595. [PMID: 28716825]

 

• Okada Y, Sonoshita M, Kakizaki F, Aoyama N, Itatani Y, Uegaki M, Sakamoto H, Kobayashi T, Inoue T, Kamba T, Suzuki A, Ogawa O, Taketo MM.
  Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer.
  Cancer Sci. 2017 Apr;108(4):744-752. [PMID: 28178391]

 

• Sowa Y, Kishida T, Tomita K, Yamamoto K, Numajiri T, Mazda O.
  Direct Conversion of Human Fibroblasts into Schwann Cells that Facilitate Regeneration of Injured Peripheral Nerve In Vivo.
  Stem Cells Transl Med. 2017 Apr;6(4):1207-1216. [PMID: 28186702]

 

• Sun L, Moritake T, Ito K, Matsumoto Y, Yasui H, Nakagawa H, Hirayama A, Inanami O, Tsuboi K.
  Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets.
  PLoS One. 2017 Apr 20;12(4):e0176162. [PMID: 28426747]

 

• Hino K, Horigome K, Nishio M, Komura S, Nagata S, Zhao C, Jin Y, Kawakami K, Yamada Y, Ohta A, Toguchida J, Ikeya M.
  Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
  J Clin Invest. 2017 Sep 1;127(9):3339-3352. [PMID: 28758906]

 

• Tsukagoshi M, Araki K, Yokobori T, Altan B, Suzuki H, Kubo N, Watanabe A, Ishii N, Hosouchi Y, Nishiyama M, Shirabe K, Kuwano H.
  Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins.
  Oncotarget. 2017 Jun 27;8(26):42159-42172. [PMID: 28178675]

 

• Mikamori M, Yamada D, Eguchi H, Hasegawa S, Kishimoto T, Tomimaru Y, Asaoka T, Noda T, Wada H, Kawamoto K, Gotoh K, Takeda Y, Tanemura M, Mori M, Doki Y.
  MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma.
  Sci Rep. 2017 Feb 15;7:42339. [PMID: 28198398]

 

2018

• Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.
  Development of a functional thyroid model based on an organoid culture system.
  Biochem Biophys Res Commun. 2018 Mar 4;497(2):783-789.[PMID: 29470983]

 

• Kawata T, Tada K, Kobayashi M, Sakamoto T, Takiuchi Y, Iwai F, Sakurada M, Hishizawa M, Shirakawa K, Shindo K, Sato H, Takaori-Kondo A.
  Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.
  Cancer Sci. 2018 Jan;109(1):103-111.[PMID: 29077243]

 

• Nakagawa Y, Ashihara E, Yao H, Yokota A, Toda Y, Miura Y, Nakata S, Hirai H, Maekawa T.
  Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation.
  Biochem Biophys Res Commun. 2018 Feb 5;496(2):490-496. [PMID: 29309790]

 

• Umehara H, Maekawa Y, Koizumi F, Shimizu M, Ota T, Fouad TM, Willey J, Kaito H, Shiraishi N, Nakashima D, Akinaga S, Ueno NT.
  Preclinical and phase I clinical studies of KW-2450, a dual IGF-1R/IR tyrosine kinase inhibitor, in combination with lapatinib and letrozole.
  Ther Adv Med Oncol. 2018 Jul 30;10:1758835918786858. [PMID: 30083253]

 

• Nakayama C, Fujita Y, Matsumura W, Ujiie I, Takashima S, Shinkuma S, Nomura T, Abe R, Shimizu H.
  The development of induced pluripotent stem cell-derived mesenchymal stem/stromal cells from normal human and RDEB epidermal keratinocytes.
  J Dermatol Sci. 2018 Sep;91(3):301-310.[PMID: 29933899]

 

• Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H.
  Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury
  Stem Cell Reports. 2018 Dec 11;11(6):1416-1432.[PMID: 30503258]

 

• Tsuma-Kaneko M, Sawanobori M, Kawakami S, Uno T, Nakamura Y, Onizuka M, Ando K, Kawada H.
  Iron removal enhances vitamin C-induced apoptosis and growth inhibition of K-562 leukemic cells.
  Sci Rep. 2018 Nov 26;8(1):17377.[PMID: 30478296]

 

• Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, M, Akira S, Tominaga M.Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura
  The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.
  iScience. 2018 Aug 31;6:306-318.[PMID: 30240621]

 

• Matsuo Y, Shiomi K, Sonoda D, Mikubo M, Naito M, Matsui Y, Yoshida T, Satoh Y.
  Molecular alterations in a new cell line (KU-Lu-MPPt3) established from a human lung adenocarcinoma with a micropapillary pattern.
  J Cancer Res Clin Oncol. 2018 Jan;144(1):75-87. [PMID: 29090354]

 

• Kimura H, Ouchi T, Shibata S, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K.
  Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.
  Sci Rep. 2018 Jul 3;8(1):10071.[PMID: 29968745]

 

• taba N, Noda I, Oka H, Kono Y, Okinaka K, Yokobata T, Okazaki S, Morimoto M, Shiota G.
  Hepatic cell sheets engineered from human mesenchymal stem cells with a single small molecule compound IC-2 ameliorate acute liver injury in mice.
  Regen Ther. 2018 Aug 24;9:45-57.[PMID: 30525075]

 

• Saito K, Sakaguchi M, Maruyama S, Iioka H, Putranto EW, Sumardika IW, Tomonobu N, Kawasaki T, Homma K, Kondo E.
  Stromal mesenchymal stem cells facilitate pancreatic cancer progression by regulating specific secretory molecules through mutual cellular interaction.
  J Cancer. 2018 Jul 30;9(16):2916-2929. [PMID: 30123360]

 

• Nishijima H, Kajimoto T, Matsuoka Y, Mouri Y, Morimoto J, Matsumoto M, Kawano H, Nishioka Y, Uehara H, Izumi K, Tsuneyama K, Okazaki IM, Okazaki T, Hosomichi K, Shiraki A, Shibutani M, Mitsumori K, Matsumoto M.
  Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE).
  J Autoimmun. 2018 Jan;86:75-92. [PMID: 28931462]

 

• Iizuka K, Jin C, Eshima K, Hong MH, Eshima K, Fukushima M.
  Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model.
  Drug Des Devel Ther. 2018 Mar 29;12:673-683.[PMID: 29636601]

 

• Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M.
  Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
  J Clin Invest. 2018 Dec 3;128(12):5603-5619.[PMID: 30418174]

 

• Konno M, Matsui H, Koseki J, Asai A, Kano Y, Kawamoto K, Nishida N, Sakai D, Kudo T, Satoh T, Doki Y, Mori M, Ishii H.
  Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells.
  Sci Rep. 2018 Jan 17;8(1):899.[PMID: 29343747]

 

2019

• Sato K, Niida A, Masuda T, Shimizu D, Tobo T, Kuroda Y, Eguchi H, Nakagawa T, Suzuki Y, Mimori K.
  Multiregion Genomic Analysis of Serially Transplanted Patient-derived Xenograft Tumors.
  Cancer Genomics Proteomics. 2019 Jan-Feb;16(1):21-27. [PMID: 30587497]

 

• Adachi Y, Matsuki M, Watanabe H, Takase K, Kodama K, Matsui J, Funahashi Y, Nomoto K.
  Antitumor and Antiangiogenic Activities of Lenvatinib in Mouse Xenograft Models of Vascular Endothelial Growth Factor-Induced Hypervascular Human Hepatocellular Carcinoma.
  Cancer Invest. 2019;37(4-5):185-198. [PMID: 31006280]

 

• Yabe SG, Fukuda S, Nishida J, Takeda F, Nashiro K, Okochi H.
  Induction of functional islet-like cells from human iPS cells by suspension culture.
  Regen Ther. 2019 Jan 2;10:69-76. [PMID: 30623004]

 

• Kondo J, Ekawa T, Endo H, Yamazaki K, Tanaka N, Kukita Y, Okuyama H, Okami J, Imamura F, Ohue M, Kato K, Nomura T, Kohara A, Mori S, Dan S, Inoue M.
  High-throughput screening in colorectal cancer tissue-originated spheroids.
  Cancer Sci. 2019 Jan;110(1):345-355. [PMID: 30343529]

 

• Mori K, Uchida T, Yoshie T, Mizote Y, Ishikawa F, Katsuyama M, Shibanuma M.
  A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells.
  FEBS J. 2019 Feb;286(3):459-478. [PMID: 30281903]

 

• Terada Y, Jo N, Arakawa Y, Sakakura M, Yamada Y, Ukai T, Kabata M, Mitsunaga K, Mineharu Y, Ohta S, Nakagawa M, Miyamoto S, Yamamoto T, Yamada Y.
  Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor.
  Cell Rep. 2019 Mar 5;26(10):2608-2621. [PMID: 30840885]

 

• Noguchi H, Miyagi-Shiohira C, Nakashima Y, Kinjo T, Kobayashi N, Saitoh I, Watanabe M, Shapiro AMJ, Kin T.
  Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors.
  Mol Ther Methods Clin Dev. 2019 Jan 29;13:243-252. [PMID: 30828587]

 

• Ishii N, Araki K, Yokobori T, Hagiwara K, Gantumur D, Yamanaka T, Handa T, Tsukagoshi M, Igarashi T, Watanabe A, Kubo N, Harimoto N, Masamune A, Umezawa K, Kuwano H, Shirabe K.
  Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts.
  Cancer Sci. 2019 Jan;110(1):334-344. [PMID: 30353606]

 

• Zeng X, Baba T, Hamanishi J, Matsumura N, Kharma B, Mise Y, Abiko K, Yamaguchi K, Horikawa N, Hunstman DG, Mulati K, Kitamura S, Taki M, Murakami R, Hosoe Y, Mandai M.
  Phosphorylation of STAT1 serine 727 enhances platinum resistance in uterine serous carcinoma.
  Int J Cancer. 2019 Jun 10. [PMID: 31228268]

 

• Akimoto H, Fukuda-Kawaguchi E, Duramad O, Ishii Y, Tanabe K.
  A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Diabetic Mice.
  J Diabetes Res. 2019 Oct 23;2019:9430473. [PMID: 31781669]

 

• Umeda S, Kanda M, Miwa T, Tanaka H, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y.
  Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer.
  Int J Cancer. 2019 Oct 9. [PMID: 31597194]

 

• Yoshida K, Tsuda M, Matsumoto R, Semba S, Wang L, Sugino H, Tanino M, Kondo T, Tanabe K, Tanaka S.
  Exosomes containing ErbB2/CRK induce vascular growth in premetastatic niches and promote metastasis of bladder cancer.
  Cancer Sci. 2019 Jul;110(7):2119-2132. [PMID: 31141251]

 

• Matsumoto M, Tsuneyama K, Morimoto J, Hosomichi K, Matsumoto M, Nishijima H.
  Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanism.
  Int Immunol. 2019 Oct 5. pii: dxz066. [PMID: 31586207]

 

2020

• Tomoya Aikawa, Noriko Togashi, Koichi Iwanaga, Hiroyuki Okada, Yumi Nishiya, Shinichi Inoue, Mark J Levis, Takeshi Isoyama.
  Quizartinib, a Selective FLT3 Inhibitor, Maintains Antileukemic Activity in Preclinical Models of RAS-mediated Midostaurin-Resistant Acute Myeloid Leukemia Cells.
  Oncotarget. 2020 Mar 17;11(11):943-955. [PMID: 32215183]

 

• Masaya Kato, Ichiro Onoyama, Sachiko Yoshida, Lin Cui, Keiko Kawamura, Keisuke Kodama, Emiko Hori, Yumiko Matsumura, Hiroshi Yagi, Kazuo Asanoma, Hideaki Yahata, Atsuo Itakura, Satoru Takeda, Kiyoko Kato.
  Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer.
  Int J Cancer. 2020 Mar 11. [PMID: 32159851]

 

• Satoshi Kubota, Mie Tanaka, Hiroko Endo, Yu Ito, Kunishige Onuma, Yutaka Ueda, Shoji Kamiura, Kiyoshi Yoshino, Tadashi Kimura, Jumpei Kondo, Masahiro Inoue.
  Dedifferentiation of Neuroendocrine Carcinoma of the Uterine Cervix in Hypoxia.
  Biochem Biophys Res Commun. 2020 Apr 2;524(2):398-404. [PMID: 32007268]

 

• Yann Pretemer, Shunsuke Kawai, Makoto Watanabe, Sanae Nagata, Megumi Nishio, Sakura Tamaki, Cantas Alev, Jing-Yi Xue, Zheng Wang, Kenichi Fukiage, Masako Tsukanaka, Tohru Futami, Shiro Ikegawa, Junya Toguchida.
  Human iPSC-derived hypertrophic chondrocytes reveal a mutation-specific unfolded protein response in chondrodysplasias.
  [PMID: None]

 

• Takahiro Yamanaka, Norifumi Harimoto, Takehiko Yokobori, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Dolgormaa Gantumur, Tadashi Handa, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Hiroshi Tanaka, Akira Watanabe, Norio Kubo, Kenichiro Araki, Ken Shirabe.
  Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts.
  Br J Cancer. 2020 Mar;122(7):986-994. [PMID: 32015511]

 

• Shinichi Umeda, Mitsuro Kanda, Takashi Miwa, Haruyoshi Tanaka, Chie Tanaka, Daisuke Kobayashi, Masamichi Hayashi, Suguru Yamada, Goro Nakayama, Masahiko Koike, Yasuhiro Kodera.
  Fraser Extracellular Matrix Complex Subunit 1 Promotes Liver Metastasis of Gastric Cancer.
  Int J Cancer. 2020 May 15;146(10):2865-2876. [PMID: 31597194]

 

• Minoru Matsumoto, Koichi Tsuneyama, Junko Morimoto, Kazuyoshi Hosomichi, Mitsuru Matsumoto, Hitoshi Nishijima.
  Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms.
  Int Immunol. 2020 Feb 7;32(2):117-131. [PMID: 31586207]

 

• Takuya Maeda, Shinya Kitamura, Hiroshi Nishihara, Teruki Yanagi.
  Extramammary Paget's disease patient-derived xenografts harboring ERBB2 S310F mutation show sensitivity to HER2-targeted therapies.
  Oncogene. 2020 Sep;39(36):5867-5875. [PMID: 32724160]

 

• Masahiro Kagabu, Naoto Yoshino, Tatsunori Saito, Yuki Miura, Ryosuke Takeshita, Kazuyuki Murakami, Hideki Kawamura, Tsukasa Baba, Toru Sugiyama.
  The efficacy of a third-generation oncolytic herpes simplex viral therapy for an HPV-related uterine cervical cancer model.
  Int J Clin Oncol. 2020 Nov 4. doi: 10.1007. [PMID: 33146805]

 

• Shuang Liu, Takeshi Kiyoi, Marina Ishida, Masaki Mogi.
  Assessment and Comparison of the Efficacy of Methotrexate, Prednisolone, Adalimumab, and Tocilizumab on Multipotency of Mesenchymal Stem Cells.
  Front Pharmacol. 2020 Jul 3;11:1004. [PMID: 32719606]

 

• Hiroshi Sootome, Hidenori Fujita, Kenjiro Ito, Hiroaki Ochiiwa, Yayoi Fujioka, Kimihiro Ito, Akihiro Miura, Takeshi Sagara, Satoru Ito, Hirokazu Ohsawa, Sachie Otsuki, Kaoru Funabashi, Masakazu Yashiro, Kenichi Matsuo, Kazuhiko Yonekura, Hiroshi Hirai.
  Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors.
  Cancer Res. 2020 Nov 15;80(22):4986-4997. [PMID: 32973082]

 

• Norikatsu Miyoshi, Shiki Fujino, Yusuke Takahashi, Masayoshi Yasui, Masayuki Ohue, Tsunekazu Mizushima.
  Implantation of human adipose-derived stromal cells for the functional recovery of a murine heat-damaged muscle model
  Surg Today. 2020 Dec;50(12):1699-1706. [PMID: 32720010]

 

• Yuichi Mitobe, Kazuhiro Ikeda, Wataru Sato, Yukinobu Kodama, Mitsuru Naito, Noriko Gotoh, Kanjiro Miyata, Kazunori Kataoka, Hitoshi Sasaki, Kuniko Horie-Inoue, Satoshi Inoue.
  Proliferation-associated long noncoding RNA, TMPO-AS1, is a potential therapeutic target for triple-negative breast cancer
  Cancer Sci. 2020 Jul;111(7):2440-2450. [PMID: 32437068]

 

• Chinami Masuda, Masamichi Sugimoto, Daiko Wakita, Makoto Monnai, Chisako Ishimaru, Ryo Nakamura, Mari Kinoshita, Keigo Yorozu, Mitsue Kurasawa, Osamu Kondoh, Kaname Yamamoto.
  Bevacizumab suppresses the growth of established non-small-cell lung cancer brain metastases in a hematogenous brain metastasis model.
  Clin Exp Metastasis. 2020 Feb;37(1):199-207. [PMID: 31768815]

 

• Gantumur Dolgormaa, Norifumi Harimoto, Norihiro Ishii, Takahiro Yamanaka, Kei Hagiwara, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Tadashi Handa, Takehiko Yokobori, Tetsunari Oyama, Hiroyuki Kuwano, Ken Shirabe.
  Mac-2-binding protein glycan isomer enhances the aggressiveness of hepatocellular carcinoma by activating mTOR signaling.
  Br J Cancer. 2020 Sep;123(7):1145-1153. [PMID: 32624579]

 

• Yuko Nitahara Kasahara, Mutsuki Kuraoka, Yuki Oda, Hiromi Hayashita Kinoh, Shin’ichi Takeda, Takashi Okada.
  Enhanced cell survival and therapeutic benefits of IL-10-expressing multipotent mesenchymal stromal cells for muscular dystrophy.
  Stem Cell Res Ther. 2021;12(1):105. doi: 10.1186/s13287-021-02168-1.

 

• Tanaka H, Kanda M, Miwa T, Umeda S, Sawaki K, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y.
  G protein subunit gamma 4 expression has potential of detection, prediction, and therapeutic target for liver metastasis of gastric cancer.
  Br J Cancer. 2021 Apr 14. doi: 10.1038/s41416-021-01366-1

 

2021

• Shigeharu G Yabe, Satsuki Fukuda, Junko Nishida, Fujie Takeda, Kiyoko Nashiro, Hitoshi Okochi.
  Efficient induction of pancreatic alpha cells from human induced pluripotent stem cells by controlling the timing for BMP antagonism and activation of retinoic acid signaling.
  PLoS One. 2021 Jan 11;16(1):e0245204. [PMID: 33428669]

 

2022

• Kim DS, Na HS, Cho KH, Lee KH, Choi J, Kwok SK, Bae YS, Cho ML, Park SH.
  Sphingosylphosphorylcholine ameliorates experimental sjögren's syndrome by regulating salivary gland inflammation and hypofunction, and regulatory B cells.
  Immunol Lett. 2022 Aug;248:62-69. doi: 10.1016/j.imlet.2022.06.008. Epub 2022 Jun 19. PMID: 35732207