
NOD/ShiJic-scidJcl Academic Reference List
Research Use Snapshot
NOD/ShiJic-scidJcl is an immunodeficient mouse model on a NOD genetic background, characterized by severe defects in adaptive immunity with reduced innate immune function.
This strain is widely used for human cell and tumor engraftment, supporting studies in xenograft, cancer stem cell biology, metastasis, and translational oncology.
On this page, you can browse key publications by research purpose or explore the complete reference list organized by year.
🧫 Human Xenograft & PDX Modeling
Human tumor and cell engraftment applications. Representative references are listed here when clearly indicated by the publication information on this page. For the complete list, please refer to the year-based archive below.
🧬 Cancer Stem Cell & Metastasis Biology
Recurrence and metastatic potential. This category highlights cancer stem-like properties and metastasis-related research supported by immunodeficient conditions.
🧠 Immune–Vascular Interface & Lymphatic Biology
Vascular and lymphatic structure/function insights. Publications in this section highlight analyses of lymphatic–venous communications and related in vivo dynamics.
🔬 Metabolic & Translational Oncology
Biomarkers and translational evaluation. This section highlights research focused on clinically relevant biomarkers and translational oncology applications.
🧩 Immunodeficiency Platform & Model Lineage
Model positioning and experimental context. This section is intended for publications that describe immunodeficiency characteristics, platform comparisons, or model background information when available on this page.
📚 Key Publications (Timeline)
Representative publications that define the research value of NOD/ShiJic-scidJcl. Use this timeline to understand key applications at a glance, then jump to the year-based archive for full citation details.
- Study of fluid dynamics reveals direct communications between lymphatic vessels and venous blood vessels at lymph nodes of mice (2017) — see 2017
- Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma. (2022) — see 2022
- CD44-positive Cancer Stem-like Cells as a Potential Source of Peritoneal Metastasis After Surgery. (2023) — see 2023
Related CLEA Japan product: NOD/ShiJic-scidJcl
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2017
- Takeda K, Mori S, Kodama T.
Study of fluid dynamics reveals direct communications between lymphatic vessels and venous blood vessels at lymph nodes of mice
J Immunol Methods. 2017 Jun;445:1-9. doi: 10.1016/j.jim.2017.02.008. Epub 2017 Feb 22.PMID: 28237707
2022
- Nakagawa M, Yamaguchi M, Endo M, Machida Y, Hattori A, Tanzawa F, Tsutsumi S, Kitabayashi I, Kawai A, Nakatani F.
Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma.
J Bone Oncol. 2022 Apr 16;34:100430. doi: 10.1016/j.jbo.2022.100430. eCollection 2022 Jun.PMID: 35493690
2023
- Sihombing AM, Murata S, Shimoji M, Miyake T, Takebayashi K, Kodama H, Tokuda A, Kojima M, Ueki T, Kitamura N, Kitamura M, Mekata E, Tani M.
CD44-positive Cancer Stem-like Cells as a Potential Source of Peritoneal Metastasis After Surgery.
Anticancer Res. 2023 Jun;43(6):2491-2500. doi: 10.21873/anticanres.16416.PMID: 37247920
FAQ
- Q: What is included on this page?
- A: This page provides an academic reference list for NOD/ShiJic-scidJcl, along with a related product link and an inquiry link.
Q: How are the references organized?- A: References are presented in the original "References by Year" list. You can jump to each year using the year index on this page.
Q: Which years are included in the reference list on this page?- A: The reference list on this page includes publications from 2017, 2022, and 2023.
Q: Can I browse the same references by research purpose?- A: Yes. The topic-based sections above provide a research-purpose view that points to the same publications listed in the year-based archive.
Q: Where can I find the product page for NOD/ShiJic-scidJcl?- A: The product link is provided in the "Related CLEA Japan product: NOD/ShiJic-scidJcl" section on this page.
Q: How can I contact CLEA Japan about this model?- A: The "Inquiry" section on this page includes a link to the contact form for questions about NOD/ShiJic-scidJcl.


