NOD/ShiJic-scidJcl
Animals/Immunodeficiency Models/
Ordering name: NOD/ShiJic-scidJcl
Nomenclature: NOD.CB17-Prkdcscid/Jcl
Availability: Live colony
Not genetically modified animal
Characteristics
The NOD/ShiJic-scid mouse strain was established by the 10-generation progeny formation the of scid (Prkdcscid) mutant gene in the C.B-17-scid strain, found by Dr. Melvin J. Bosma at the Fox Chase Cancer Center in 1983 in NOD/Shi mice, which is a type-1 diabetes murine model supplied by the Central Institute for Experimental Medicine and Life Science (CIEM).
This strain was introduced to CLEA Japan, Inc. from the CIEM in 2006, and the production and supply of these mice as NOD/ShiJic-scid Jcl mice was started in 2007.
※The following are the formal names for each animal in our company:
*1 BALB/cAJcl-nu/nu、 *2 C.B-17/Icr-scid/scidJcl、 *3 NOD/ShiJic-scidJcl
Background Data (weight, blood property, blood biochemistry, organ weight)
◆ NOD/ShiJic-scidJcl: 10-week data (*Japanese) 
◆ NOD/ShiJic-scidJcl: 10-week data (*Japanese) 
Rearing management of immunodeficiency models
Microbiological control of immunodeficiency model animals should be managed strictly because of their properties. Due caution is necessary against opportunistic infections with normal inhabitant microorganisms as well as microorganisms that are pathogenic in mice and rats.
- Requiring workers to wear specialized protective clothing that covers all exposed skin and to use respiratory filters.
- Supply of boiled and chlorine-added water and autoclaved diet (CL-2)
- Prevention of falling bacteria using filter caps and handling animals using tweezers or disposable gloves
Detailed Catalog (PDF)
Some of the materials in the PDF document are excerpted here.
▼ NK activity
▼ Impaired macrophage function
▼ For more details(*Japanese) ▼
Our Contract Research Services related with This Animal
For details on our contract research services, including cryopreserved embryos, contracted testing, and the provision of research materials such as blood and organs, please click here .