C.B-17/Icr-scid/scidJcl Academic Reference List
Research Use Snapshot
C.B-17/Icr-scid/scidJcl is a classic SCID mouse strain characterized by profound adaptive immunodeficiency, providing a stable in vivo platform for xenotransplantation and heterologous cell engraftment.
Publications on this page demonstrate applications in xenogeneic bone marrow and chimeric system construction, tumor biology under oxidative stress regulation and in vivo tumor evaluation, human erythrocyte–based hematology models, as well as tissue engineering and functional recovery research.
You can explore key publications by research purpose or browse the complete reference list organized by year.
🧫 Xenotransplantation & Chimeric Systems
Xenogeneic tissues and cells in immunodeficient recipients. This section highlights applications of C.B-17/Icr-scid/scidJcl mice as recipients for xenogeneic systems, including ectopic bone marrow structure construction and chimerism-related research.
🧬 Tumor Biology & Oxidative Stress Control
Tumor survival mechanisms and in vivo tumor evaluation. Publications in this category cover oxidative stress regulation, antibody-mediated anti-tumor activity, and tumor-targeted diagnostic probe evaluation under immunodeficient conditions.
- Overexpression of manganese superoxide dismutase gene suppresses spontaneous apoptosis without a resultant alteration in in vivo growth of the mouse fibrosarcoma, FSa-II (2000) — see 2000
- Mouse-human chimeric anti-Tn IgG1 induced anti-tumor activity against Jurkat cells in vitro and in vivo (2008) — see 2008
- Novel technetium-99m-labeled bivalent PSMA-targeting probe based on hydroxamamide chelate for diagnosis of prostate cancer (2024) — see 2024
🩸 Hematology & Hemoparasite Model Support
Human erythrocyte acceptability and blood model development. This section features studies evaluating erythrocyte compatibility, supporting hemoparasite-related research and comparative hematological model development.
🦷 Tissue Engineering & Regenerative Research
Reconstruction of complex tissue structures under immunodeficient conditions. References here demonstrate tissue engineering applications, including reconstructed tooth germ elements and induced enamel/dentin complexes.
🧠 Neurology & Functional Recovery Models
Neurological outcomes and functional recovery evaluation. This category includes studies assessing behavioral and structural outcomes following cerebral ischemic injury.
📚 Key Publications (Timeline)
Representative publications that define the research versatility of C.B-17/Icr-scid/scidJcl mice. Use this timeline to quickly understand how this model has been applied across diverse research fields, then jump to the year-based archive for full citation details.
- Overexpression of manganese superoxide dismutase gene suppresses spontaneous apoptosis without a resultant alteration in in vivo growth of the mouse fibrosarcoma, FSa-II (2000) — see 2000
- Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism by engraftment of rat bone marrow plugs into mouse kidney capsules (2003) — see 2003
- Erythrocyte-replaced mouse model for Haemoparasite studies: comparison of NOD/shi-scid and C.B-17/Jcl-scid mouse upon acceptability of human erythrocytes (2003) — see 2003
- The induction of enamel and dentin complexes by subcutaneous implantation of reconstructed human and murine tooth germ elements (2004) — see 2004
- Mouse-human chimeric anti-Tn IgG1 induced anti-tumor activity against Jurkat cells in vitro and in vivo (2008) — see 2008
- Novel technetium-99m-labeled bivalent PSMA-targeting probe based on hydroxamamide chelate for diagnosis of prostate cancer (2024) — see 2024
Related CLEA Japan product: C.B-17/Icr-scid/scidJcl
Related CLEA Japan product: C.B-17/Icr-scid/scidJcl
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2000
- Kuroda M, Himei K, St Clair DK, Urano M, Yoshino T, Akagi T, Asaumi J, Akaki S, Takeda Y, Kanazawa S, Hiraki Y.
Overexpression of manganese superoxide dismutase gene suppresses spontaneous apoptosis without a resultant alteration in in vivo growth of the mouse fibrosarcoma, FSa-II
Anticancer Res. 2000 Jan-Feb;20(1A):7-10. PMID: 10769628
2003
- Hara H, Ohdan H, Tokita D, Onoe T, Zhou W, Asahara T.
Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism by engraftment of rat bone marrow plugs into mouse kidney capsules
Xenotransplantation. 2003 May;10(3):259-66. doi: 10.1034/j.1399-3089.2003.02026.x. PMID: 12694546
- Ishihara C, Zamoto A, Tsuji M, Wei Q, Azuma I, Hioki K.
Erythrocyte-replaced mouse model for Haemoparasite studies: comparison of NOD/shi-scid and C.B-17/Jcl-scid mouse upon acceptability of human erythrocytes
J Vet Med Sci. 2003 Aug;65(8):831-7. doi: 10.1292/jvms.65.831. PMID: 12951413
2004
- Isogawa N, Terashima T, Nakano Y, Kindaichi J, Takagi Y, Takano Y.
The induction of enamel and dentin complexes by subcutaneous implantation of reconstructed human and murine tooth germ elements
Arch Histol Cytol. 2004 Mar;67(1):65-77. doi: 10.1679/aohc.67.65. PMID: 15125024
2008
- Ando H, Matsushita T, Wakitani M, Sato T, Kodama-Nishida S, Shibata K, Shitara K, Ohta S.
Mouse-human chimeric anti-Tn IgG1 induced anti-tumor activity against Jurkat cells in vitro and in vivo
Biol Pharm Bull. 2008 Sep;31(9):1739-44. doi: 10.1248/bpb.31.1739. PMID: 18758069
2021
- Yamaguchi N, Sawano T, Fukumoto K, Nakatani J, Inoue S, Doe N, Yanagisawa D, Tooyama I, Nakagomi T, Matsuyama T, Tanaka H.
Voluntary running exercise after focal cerebral ischemia ameliorates dendritic spine loss and promotes functional recovery
Brain Res. 2021 Sep 15;1767:147542. doi: 10.1016/j.brainres.2021.147542. Epub 2021 May 30. PMID: 34077764
2024
- Shimizu Y, Ando M, Watanabe H, Ono M.
Novel technetium-99m-labeled bivalent PSMA-targeting probe based on hydroxamamide chelate for diagnosis of prostate cancer
Ann Nucl Med. 2024 Oct;38(10):847-851. doi: 10.1007/s12149-024-01959-9. Epub 2024 Jul 8. PMID: 38976087
FAQ
- Q: What is included on this page?
- A: This page provides an academic reference list for C.B-17/Icr-scid/scidJcl, along with a related product link and an inquiry link.
Q: How are the references organized?- A: References are presented in the original "References by Year" list. You can jump to each year using the year index on this page.
Q: Which years are included in the reference list on this page?- A: The reference list on this page includes publications from 2000, 2003, 2004, 2008, 2021, and 2024.
Q: Can I browse the same references by research purpose?- A: Yes. The topic-based sections above provide a research-purpose view that points to the same publications listed in the year-based archive.
Q: Where can I find the product page for C.B-17/Icr-scid/scidJcl?- A: The product link is provided in the "Related CLEA Japan product: C.B-17/Icr-scid/scidJcl" section on this page.
Q: How can I contact CLEA Japan about this model?- A: The "Inquiry" section on this page includes a link to the contact form for questions about C.B-17/Icr-scid/scidJcl.
