F344/NJcl-rnu/rnu Academic Reference List
Research Use Snapshot
- Immunodeficiency: T-cell–deficient nude rat background
- Evidence on this page: Publications covering immunology, toxicology, carcinogenesis, and transplantation-related research
- How to browse: Use topic-based sections below or the original year-based list
🔬 Cancer & Xenograft Studies
Why use F344/NJcl-rnu/rnu for cancer and xenograft research? The reference list on this page includes studies on carcinogenesis and cancer-related immune mechanisms in this immunodeficient rat strain.
🧪 Toxicology & Carcinogenicity
Applications in toxicology and safety assessment. This page includes publications evaluating pathological responses in F344/NJcl-rnu/rnu rats under specific experimental conditions.
🧠 Immunology & Inflammation
Immune mechanisms under T-cell–deficient conditions. The publications listed on this page include studies on immune-related mechanisms, immune disease models, and antigen presentation.
- Prevention of adult T-cell leukemia-like lymphoproliferative disease in rats by adoptively transferred T cells... (2000) — see 2000
- Immunological aspects of rat models of HTLV type 1-infected T lymphoproliferative disease (2000) — see 2000
- Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia (2001) — see 2001
- Bromodeoxyuridine labeling studies on the proliferation of intestinal mucosal mast cells in normal and athymic rats (1990) — see 1990
🧬 Genetic Background & Model Development
Strain characteristics and model development. This section highlights publications focusing on transplantation systems and foundational model-building work listed on this page.
- Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism... (2003) — see 2003
- Over expression of bone morphogenetic protein-3b (BMP-3b) using an adenoviral vector... (2003) — see 2003
- The effects of CD133-positive cells to a nonvascularized fasciocutaneous free graft in the rat model (2009) — see 2009
- Cryopreserved human adipose-derived stromal vascular fraction maintains fracture healing potential... (2021) — see 2021
📚 Key Publications (Timeline)
Key publications highlighting the scientific legacy of this model. Use this quick timeline to jump to the year-based sections below (the original “References by Year” list remains unchanged).
- 1990 — Early immunology-related publication
- 2000 — Immune disease models and toxicological response
- 2001 — Antigen presentation and immune mechanism
- 2003 — Transplantation systems / model-building studies
- 2006 — Carcinogenesis under T-cell deficiency
- 2009 — Cell-based evaluation study
- 2021 — Translational regenerative medicine
Related CLEA Japan product: F344/NJcl-rnu/rnu
References by Year
Related CLEA Japan product: F344/NJcl-rnu/rnu
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1990
- Arizono N, Shiota T, Yamada M, Matsumoto Y, Yoshikawa H, Matsuda S, Tegoshi T.
Bromodeoxyuridine labeling studies on the proliferation of intestinal mucosal mast cells in normal and athymic rats
APMIS. 1990 Apr;98(4):369-76. doi: 10.1111/j.1699-0463.1990.tb01046.x.PMID: 2354054
2000
- Miyata M, Sakuma F, Ito M, Ohira H, Sato Y, Kasukawa R.
Athymic nude rats develop severe pulmonary hypertension following monocrotaline administration
Int Arch Allergy Immunol. 2000 Mar;121(3):246-52. doi: 10.1159/000024324.PMID: 10729784
- Ohashi T, Hanabuchi S, Kato H, Tateno H, Takemura F, Tsukahara T, Koya Y, Hasegawa A, Masuda T, Kannagi M.
Prevention of adult T-cell leukemia-like lymphoproliferative disease in rats by adoptively transferred T cells from a donor immunized with human T-cell leukemia virus type 1 Tax-coding DNA vaccine
J Virol. 2000 Oct;74(20):9610-6. doi: 10.1128/jvi.74.20.9610-9616.2000.PMID: 11000233
- Kannagi M, Ohashi T, Hanabuchi S, Kato H, Koya Y, Hasegawa A, Masuda T, Yoshiki T.
Immunological aspects of rat models of HTLV type 1-infected T lymphoproliferative disease
AIDS Res Hum Retroviruses. 2000 Nov 1;16(16):1737-40. doi: 10.1089/08892220050193236.PMID: 11080819
2001
- Ito A, Shinkai M, Honda H, Wakabayashi T, Yoshida J, Kobayashi T.
Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia
Cancer Immunol Immunother. 2001 Dec;50(10):515-22. doi: 10.1007/s00262-001-0233-7.PMID: 11776373
2003
- Hara H, Ohdan H, Tokita D, Onoe T, Zhou W, Asahara T.
Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism by engraftment of rat bone marrow plugs into mouse kidney capsules
Xenotransplantation. 2003 May;10(3):259-66. doi: 10.1034/j.1399-3089.2003.02026.x.PMID: 12694546
- Kaihara S, Bessho K, Okubo Y, Sonobe J, Komatsu Y, Miura M, Miyatake S, Nakao K, Iizuka T.
Over expression of bone morphogenetic protein-3b (BMP-3b) using an adenoviral vector promote the osteoblastic differentiation in C2C12 cells and augment the bone formation induced by bone morphogenetic protein-2 (BMP-2) in rats
Life Sci. 2003 Feb 28;72(15):1683-93. doi: 10.1016/s0024-3205(02)02477-3.PMID: 12559390
2006
- Wu B, Ootani A, Iwakiri R, Sakata Y, Fujise T, Amemori S, Yokoyama F, Tsunada S, Toda S, Fujimoto K.
T cell deficiency leads to liver carcinogenesis in azoxymethane-treated rats
Exp Biol Med (Maywood). 2006 Jan;231(1):91-8. doi: 10.1177/153537020623100111.PMID: 16380649
2009
- Nakanishi M, Ishikawa M, Sunagawa T, Yokota K, Asahara T, Ochi M.
The effects of CD133-positive cells to a nonvascularized fasciocutaneous free graft in the rat model
Ann Plast Surg. 2009 Sep;63(3):331-5. doi: 10.1097/SAP.0b013e3181934951.PMID: 19700960
2021
- Kamenaga T, Kuroda Y, Nagai K, Tsubosaka M, Takashima Y, Kikuchi K, Fujita M, Ikuta K, Anjiki K, Maeda T, Nakano N, Takayama K, Hashimoto S, Hayashi S, Matsushita T, Niikura T, Kuroda R, Matsumoto T.
Cryopreserved human adipose-derived stromal vascular fraction maintains fracture healing potential via angiogenesis and osteogenesis in an immunodeficient rat model
Stem Cell Res Ther. 2021 Feb 4;12(1):110. doi: 10.1186/s13287-021-02182-3.PMID: 33541427
FAQ
Q:What is included on this page?
A:This page provides an academic reference list for F344/NJcl-rnu/rnu, including a related product link and publications organized by year.
Q:How are the references organized?
A:References are presented in the original "References by Year" list. You can jump to each year using the year index at the top of the page.
Q:Can I browse the same references by research purpose?
A:Yes. The topic-based sections above provide a research-purpose view that points to the same publications listed in the year-based reference list.
Q:Where can I find the product page for F344/NJcl-rnu/rnu?
A:The product link is provided in the "Related CLEA Japan product: F344/NJcl-rnu/rnu" section on this page.
Q:How can I contact CLEA Japan about this model?
A:The "Inquiry" section on this page includes a link to the contact form for questions about F344/NJcl-rnu/rnu.
