BALB/cAJcl-nu/nu Academic Reference List
Research Use Snapshot
BALB/cAJcl-nu/nu is a classic nude mouse model with T-cell deficiency, widely used as a standard platform for human tumor xenograft studies.
Publications on this page highlight applications in radiotracer imaging and dosimetry, radiotherapy enhancement using nanoparticles and antibody-based approaches, as well as wound healing and regenerative medicine under immunodeficient conditions.
You can explore key publications by research purpose or browse the complete reference list organized by year.
🧫 Xenograft Oncology Platform
Standard xenograft platform for tumor growth and therapy response evaluation. This section highlights studies using BALB/cAJcl-nu/nu mice in solid tumor models and treatment assessments.
☢️ Radiotracer Imaging & Dosimetry
Radiotracer biodistribution, PET imaging, and dosimetry. Publications in this category demonstrate nuclear medicine–related applications evaluated in nude mice.
🥇 Nanomedicine & Radiosensitization
Advanced radiotherapy enhancement strategies. This section features studies exploring nanoparticle- and antibody-based approaches to enhance tumor control in vivo.
🩹 Regenerative Medicine & Wound Healing
Human cell–based repair under immunodeficient conditions. References here demonstrate applications in wound healing and regenerative medicine, including radiation-induced ulcer models.
🧪 Host Factors: Metabolism & Nutrition Effects
Host environment influences on biology and responses. This category includes studies examining metabolic and nutritional factors and their impact on disease-related outcomes.
- Comparison of the Effects of 3 Forms of Soluble Dietary Fiber on the Production of IgA in BALB/cAJcl and BALB/cAJcl-nu/nu Mice. (2023) — see 2023
- High glucose enhances the aggressiveness of lung adenocarcinoma via activating epidermal growth factor receptor/signal transducer and activator of transcription 3 pathways. (2023) — see 2023
📚 Key Publications (Timeline)
Representative publications that illustrate the research value of BALB/cAJcl-nu/nu mice. Use this timeline to quickly grasp how this model has been applied across different research fields, then jump to the year-based archive for full citation details.
- Fluorine-18-labeled 5-fluorouracil is a useful radiotracer for differentiation of malignant tumors from inflammatory lesions. (2008) — see 2008
- Biodistribution and radiation dosimetry of [¹⁸F]-5-fluorouracil. (2013) — see 2013
- Comparison of the Effects of 3 Forms of Soluble Dietary Fiber on the Production of IgA in BALB/cAJcl and BALB/cAJcl-nu/nu Mice. (2023) — see 2023
- High glucose enhances the aggressiveness of lung adenocarcinoma via activating epidermal growth factor receptor/signal transducer and activator of transcription 3 pathways. (2023) — see 2023
- Gold Nanoparticles Enhance the Tumor Growth-Suppressing Effects of Cetuximab and Radiotherapy in Head and Neck Cancer In Vitro and In Vivo. (2023) — see 2023
- Human Adipose-Derived Endothelial Progenitor Cells Accelerate Epithelialization of Radiation Ulcers in Nude Mice. (2024) — see 2024
- Efficacy of metformin and verteporfin treatment alone or in combination in a murine head and neck cancer xenograft model. (2025) — see 2025
Related CLEA Japan product: BALB/cAJcl-nu/nu
Related CLEA Japan product: BALB/cAJcl-nu/nu
For the animal, please click here↓
: https://www.clea-japan.com/en/products/immunodeficiency/item_a0010
Inquiry:
If you have any question, please feel free to contact us from here .
2008
- Sugae S, Suzuki A, Takahashi N, Minamimoto R, Cheng C, Theeraladanon C, Endo I, Togo S, Inoue T, Shimada H.
Fluorine-18-labeled 5-fluorouracil is a useful radiotracer for differentiation of malignant tumors from inflammatory lesions.
Ann Nucl Med. 2008 Jan;22(1):65-72. doi: 10.1007/s12149-007-0081-4.
2013
- Hino-Shishikura A, Suzuki A, Minamimoto R, Shizukuishi K, Oka T, Tateishi U, Sugae S, Ichikawa Y, Horiuchi C, Inoue T.
Biodistribution and radiation dosimetry of [¹⁸F]-5-fluorouracil.
Appl Radiat Isot. 2013 May;75:11-7. doi: 10.1016/j.apradiso.2013.01.014. Epub 2013 Jan 20.
2023
- Matsumoto K, Sawano H, Otsubo M, Yui A.
Comparison of the Effects of 3 Forms of Soluble Dietary Fiber on the Production of IgA in BALB/cAJcl and BALB/cAJcl-nu/nu Mice.
J Nutr. 2023 May;153(5):1618-1626. doi: 10.1016/j.tjnut.2023.03.037. Epub 2023 Apr 1.
- Sorin S, Zhou Y, Thithuan K, Khawkhiaw K, Zeng F, Ruangpratyakul T, Chomphoo S, Seubwai W, Wongkham S, Saengboonmee C.
High glucose enhances the aggressiveness of lung adenocarcinoma via activating epidermal growth factor receptor/signal transducer and activator of transcription 3 pathways.
J Nutr Biochem. 2023 Sep;119:109399. doi: 10.1016/j.jnutbio.2023.109399. Epub 2023 Jun 2.
- Sato T, Kakei Y, Hasegawa T, Kashin M, Teraoka S, Yamaguchi A, Sasaki R, Akashi M.
Gold Nanoparticles Enhance the Tumor Growth-Suppressing Effects of Cetuximab and Radiotherapy in Head and Neck Cancer In Vitro and In Vivo.
Cancers (Basel). 2023 Dec 3;15(23):5697. doi: 10.3390/cancers15235697.
2024
- Mori M, Saito N, Shirado T, Wu Y, Asahi R, Yoshizumi K, Yamamoto Y, Zhang B, Yoshimura K.
Human Adipose-Derived Endothelial Progenitor Cells Accelerate Epithelialization of Radiation Ulcers in Nude Mice.
Plast Reconstr Surg. 2024 Mar 1;153(3):625-635. doi: 10.1097/PRS.0000000000010756. Epub 2023 May 24.
2025
- Shan AP, Hlaing KS, Leelahavanichkul A, Amornphimoltham P.
Efficacy of metformin and verteporfin treatment alone or in combination in a murine head and neck cancer xenograft model.
Eur J Oral Sci. 2025 Feb;133(1):e13034. doi: 10.1111/eos.13034. Epub 2025 Jan 8. PMID: 39780329
FAQ
- Q: What is included on this page?
- A: This page provides an academic reference list for BALB/cAJcl-nu/nu, along with a related product link and an inquiry link.
Q: How are the references organized?- A: References are presented in the original "References by Year" list. You can jump to each year using the year index on this page.
Q: Which years are included in the reference list on this page?- A: The reference list on this page includes publications from 2008, 2013, 2023, 2024, and 2025.
Q: Can I browse the same references by research purpose?- A: Yes. The topic-based sections above provide a research-purpose view that points to the same publications listed in the year-based archive.
Q: Where can I find the product page for BALB/cAJcl-nu/nu?- A: The product link is provided in the "Related CLEA Japan product: BALB/cAJcl-nu/nu" section on this page.
Q: How can I contact CLEA Japan about this model?- A: The "Inquiry" section on this page includes a link to the contact form for questions about BALB/cAJcl-nu/nu.
