Made in Thailand. Contact and other details information can be found here. Introducing CLEA Japan's SPF/model experimental animals.
Since 2023, Nomura Siam International Co, Ltd. (NSI) and CLEA Japan, Inc. (CLEA Japan) have planned to focus on expanding sales in the Southeast Asian market. On top of that, we are promoting high-quality laboratory animals that meet global standards, starting from the breeding facility M-CBC in Thailand.
Because of local production in Thailand, it is possible to deliver close to your request schedule and certainty that is more flexible than importing. In Thai-speaking, you can contact us using the ways below.
Phone number:
+66-2168-8706
Mail address:
info@nomurasiam.com
▼ NSI(Nomura Siam International Co, Ltd.) Web
▼ Inquiry here
Diabetes model
Stable diabetes model without DIO (Diet induced obesity):SDT
SDT rat develops diabetes with a higher degree of stability than GK/Jcl rats without DIO. It has a high survival rat up to 65 weeks of age and can be used for long-term studies. Since we ship from our facility in Thailand, we can deliver quickly with low cost to Thailand, Singapore, Malaysia, and other Asian countries.
Immunodeficiency Models
M-CBC has successfully produced immunodeficient animals that require higher microbial control than general purpose SPF animal models.Currently, we can breed and provide three representative immunodeficient animals.
| Characteristics | BALA/cA-nu/nu | C.B-17-scid | NOD-scid |
| Immune cell abnormalities | T cell deficiency | T/B cell deficiency | T/B cell deficiency |
| NK cell activity | Normal | Normal | Reduce |
| Complement activity | Normal | Normal (slightly enhanced) | Reduce |
| Macrophage function | Normal | Normal | Reduce |
| Immunoglobulin production |
IgA: low IgM: normal IgG: there are individual difference |
Generally, not produced. However, Leaky8Ig+ animals may appear in few precents |
Generally, not produced |
| Factors of primary immunodeficiency | Due to abnormality of the thymic epithelium | Due to inability to rearrange the antigen receptor gene | Inability to rearrange antigen receptor genes and multiple immunodeficiencies |
| Anatomical/histological features |
The thymus is absent, but lymph nodes are present. |
Both thymus and lymph nodes are present but extremely small | Both thymus and lymph nodes are present but extremely small |
Immunodeficient animals lacking T cell function: BALB/cA-nu/nu
It lacks T cell function and has many achievements in various immunological and cancer research, anticancer drug screening and microbiological research.
Lack of B cell function to match T cells: C.B-17-scid
In addition to cellular immunity, little immunoglobulin is produced due to the lack of T-cell and B-cell function. A wider range of cell can be successfully engrafted with almost the same budged as BALB/cA-nu/nu.
Decreased NK activity, complement activity, and macrophage function along with the lack of T/B cell function: NOD-scid
In addition to the lack of T and B cells in SCID mice, NOD strain-derived complement activity and decreased macrophage function were added. It is a severer immunodeficient animal model than C.B-17-scid and has excellent engraftment nature of allogeneic and heterogeneous cells.
Rat model (Jcl:Wistar / Jcl:SD)
We produce general purpose laboratory rats with SPF conditions that meet global standards, which are scarcity in Southeast Asia. It is widely used, especially in injection drug administration tests.
Wistar rat:
Wistar rat is medium-sized albinos with a good sensitivity to various factors. Their learning ability is particularly high. It is used for studies in a variety of fields including behavioral pharmacology, toxicity, pharmacology, drug efficacy, and safety testing.
SD rat:
SD has many test results and there is no risk of hydronephrosis like Wistar. It is ideal for injection test and has already been used in a wide range of research fields, including safety testing, pharmacology, toxicity, biochemistry, nutrition, and other.
Procedure
NSI will oversee sales and delivery arrangements to Thailand.
1. Contact us by inquiry form of this website.
2. Have a meeting with the NSI sales representative. Please let us know the following.
・Preferred animals strain/type
・Number of animals, Male___ Female___
・Week of age
・Date of delivery
・Place of delivery (Detailed as needed)
3. Arrange delivery schedule by NSI.
4. Prepare animals as arranged schedule.
5. We will ship from M-CBC.
6. Delivery completed
Two sizes of boxes can be chosen. These can safely transport animals with SPF condition.
7. Payment
Pay by wire transfer to the designated account.
FAQ
From which facility of the animals in Japan or Thailand will be delivered?
If the strain you are considering is produced at MCBC, we basically recommend delivering from there for Southeast Asian and India customers because of the advantages in cost and transportation time.The strain produced only in Japan will be delivered from Japan.
Are there any differences between animals produced at facilities in Japan and Thailand?
At MCBC, we use the same feed as in Japan, and the manager of MCBC has an experience the same position in Japanese facility.
In addition, we are monitoring the animals through microbiological at the Central Institute for Experimental Animals every three months and genetic monitoring every three years, as same as Japanese facility animals.
We expect the quality is enough to be considered as the same between Japanese and Thai animals.
Inquiry to NSI:
▼ NSI (Nomura Siam International Co, Ltd.)
Inquiry
If you have any question, please feel free to contact us from below.
