SDT/Jcl Academic Reference List
The SDT/Jcl Academic Reference Archive provides a curated collection of scientific publications featuring the SDT/Jcl rat supplied by CLEA Japan.
As a spontaneous non-obese type 2 diabetes model, SDT/Jcl has been widely utilized to investigate chronic hyperglycemia, diabetic complications, pancreatic pathology, ocular disease, nephropathy, neuropathy, and the long-term progression of diabetes mellitus. The model is also valuable for evaluating antidiabetic therapies and disease mechanisms.
The references collected on this page demonstrate its broad application across studies involving glucose metabolism, diabetic microvascular complications, pharmacological evaluation, endocrine function, and translational diabetes research. Publications are organized chronologically, allowing researchers to explore the historical development and expanding scientific applications of this model.
For detailed information on the biological characteristics, availability, and ordering information for SDT/Jcl, please visit the corresponding product page.
Research Use Snapshot
- Non-obese type 2 diabetes: SDT/Jcl is a spontaneously diabetic non-obese Torii rat strain used to study hyperglycemia and disease progression without obesity-driven confounding.
- Severe ocular complications: Publications on this page include foundational work and intervention studies related to diabetic retinopathy, cataract, and retinal pathology.
- Multi-organ complications: References also cover nephropathy, neuropathy, vascular dysfunction, and systemic pathology relevant to chronic diabetes.
- How to browse: Use the topic sections below for representative studies by research purpose, or use the year index to access the complete reference list.
🩺 Non-Obese Type 2 Diabetes & Metabolic Dysregulation
Non-obese diabetes and metabolic progression. SDT/Jcl is a spontaneously diabetic non-obese model used to characterize disease onset, progression, and metabolic abnormalities in type 2 diabetes.
- A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications. (2000) — see 2000
- Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat. (2003) — see 2003
- Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats. (2004) — see 2004
- The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications. (2013) — see 2013
👁️ Retinopathy & Retinal–CNS / Neurodegeneration Axis
Ocular complications and neural involvement. Publications in this section include foundational characterization and intervention studies in diabetic retinopathy, cataract, and retinal pathology in SDT rats.
- Characteristics of diabetic retinopathy in SDT rats. (2006) — see 2006
- Preventive effects of glycemic control on ocular complications of Spontaneously Diabetic Torii rat. (2006) — see 2006
- Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model. (2007) — see 2007
- Effects of long-term treatment with ranirestat, a potent aldose reductase inhibitor, on diabetic cataract and neuropathy in spontaneously diabetic Torii rat. (2013) — see 2013
- Improvement in Diabetic Retinopathy through Protection against Retinal Apoptosis in Spontaneously Diabetic Torii Rats (Osteomeles schwerinae extract). (2019) — see 2019
🫀 Oxidative Stress, Microvascular Injury & Tissue Fibrosis
Shared mechanisms across diabetic complications. These studies focus on oxidative stress and vascular injury mechanisms that contribute to progressive diabetic complications in SDT rats.
- Anti-oxidative effect of vitamin D analog on incipient vascular lesion in non-obese type 2 diabetic rats. (2013) — see 2013
- Vitamin D Activates the Nrf2-Keap1 Antioxidant Pathway and Ameliorates Nephropathy in Diabetic Rats. (2013) — see 2013
- Epoetin beta pegol ameliorates flow-mediated dilation with improving endothelial nitric oxide synthase coupling state in nonobese diabetic rats. (2017) — see 2017
🫘 Pancreas / Islet Pathology, Inflammation & β-Cell Injury
Islet pathology and transplantation-related evidence. This section highlights pancreas/islet-related studies and transplantation work listed on this page, supporting investigation of β-cell injury and recovery mechanisms in SDT rats.
- Stage-dependent effect of pancreatic transplantation on diabetic ocular complications in the Spontaneously Diabetic Torii rat. (2004) — see 2004
- Beneficial Effects of Pancreas Transplantation: Regeneration of Pancreatic Islets in the Spontaneously Diabetic Torii rat. (2005) — see 2005
- Development of islet-like cell clusters after pancreas transplantation in the spontaneously diabetic Torii rat. (2005) — see 2005
🦴 Bone–Vascular Cross-Talk & Systemic Complications
Systemic pathology and organ cross-talk in chronic diabetes. Publications here highlight systemic complications and organ cross-talk, including kidney-related pathology and mineral/bone disorder features reported in SDT rats.
- Diabetic Nephropathy in Spontaneously Diabetic Torii (SDT) Rats. (2011) — see 2011
- Newly Developed Rat Model of Chronic Kidney Disease-Mineral Bone Disorder. (2017) — see 2017
- Urothelial hyperplasia with calculi (papillomatosis) in the urinary bladder of a male spontaneous diabetic Torii rat. (2019) — see 2019
📚 Key Publications (Timeline)
Representative studies that help you understand SDT/Jcl at a glance. Use this timeline to quickly grasp how SDT/Jcl has been characterized as a non-obese type 2 diabetes model and applied to complication research over time.
- A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications. (2000) — see 2000
- Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats. (2004) — see 2004
- Characteristics of diabetic retinopathy in SDT rats. (2006) — see 2006
- The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications. (2013) — see 2013
- Effects of long-term treatment with ranirestat on diabetic cataract and neuropathy in spontaneously diabetic Torii rat. (2013) — see 2013
- Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and preventive efficacy (uPA receptor system). (2017) — see 2017
- Improvement in Diabetic Retinopathy through protection against retinal apoptosis (Osteomeles schwerinae extract). (2019) — see 2019
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References by Year
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2000
- Shinohara M, Masuyama T, Shoda T, Takahashi T, Katsuda Y, Komeda K, Kuroki M, Kakehashi A, Kanazawa Y.
A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications.
Int J Exp Diabetes Res. 2000; 1(2): 89-100. [PMID: 11469401]
2001
- 梯 彰弘, 金澤 康徳.
新しい糖尿病網膜症モデル動物-SDTラット.
内分泌･糖尿病科. 2001; 12(4): 386-90.
- 益山 拓, 布施 雅規, 原 朱美, 菅原 盛幸, 金澤 真雄, 金澤 康徳, 米田 嘉重郎.
2型糖尿病モデルSDTラットの耐糖能低下に関する遺伝学的解析.
Diabetes Frontier. 2001; 12: 818-9.
2002
- 篠原 雅巳, 益山 拓, 正田 俊之, 米田 嘉重郎, 梯 彰弘, 黒木 昌寿, 金澤 康徳.
新しい糖尿病モデルSDT(Spontaneously Diabetic Torii)ラットについて.
Diabetes Frontier. 2002; 13(1): 112-3.
- 金澤 康徳, 米田 嘉重郎.
糖尿病実験モデル動物－概論.
日本臨牀. 2002; 60(増刊8): 19-24. [PMID: 12355745]
- 鈴木 進, 檜尾 好徳.
非肥満糖尿病モデル動物.
日本臨牀. 2002; 60(増刊8): 33-7. [PMID: 12355768]
- 梯 彰弘.
シンポジウム4 糖尿病動物モデルとその臨床的意義 -4糖尿病合併症動物モデル：網膜症を中心に.
糖尿病学の進歩. 2002; 36: 318-23.
2003
- Masuyama T, Fuse M, Yokoi N, Shinohara M, Tsujii H, Kanazawa M, Kanazawa Y, Komeda K, Taniguchi K.
Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat.
Biochem Biophys Res Commun. 2003; 304(1): 196-206. [PMID: 12705906]
- 梯 彰弘.
糖尿病網膜症の形態学とモデル動物からみた糖尿病網膜症の発症機序.
内分泌･糖尿病科. 2003; 17(1): 31-7.
2004
- Masuyama T, Komeda K, Hara A, Noda M, Shinohara M, Oikawa T, Kanazawa Y, Taniguchi K.
Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats.
Biochem Biophys Res Commun. 2004; 314(3): 870-7. [PMID: 14741717]
- 篠原 雅巳, 正田 俊之, 及川 寿浩, 益山 拓, 高橋 統一, 勝田 佳朋, 米田 嘉重郎, 佐藤 嘉兵, 金澤 康徳.
自然発症2型糖尿病モデル雌性SDTラットの糖尿病病態について.
糖尿病. 2004; 47(2): 111-6.
- 和田 龍一, 矢島 信久, 篠原 雅巳, 八木橋 操六.
新しい非肥満２型糖尿病モデルSpontaneously Diabetic Torii (SDT)ラットの末梢神経障害.
Diabetes Frontier. 2004; 15(5): 731.
- Miao G, Ito T, Uchikoshi F, Kamei M, Akamaru Y, Kiyomoto T, Komoda H, Nozawa M, Matsuda H.
Stage-dependent effect of pancreatic transplantation on diabetic ocular complications in the Spontaneously Diabetic Torii rat.
Transplantation. 2004; 77(5): 658-63. [PMID: 15021825]
- Shinohara M, Oikawa T, Sato K, Kanazawa Y.
Glucose intolerance and hyperlipidemia prior to diabetes onset in female Spontaneously Diabetic Torii (SDT) rats.
Exp Diabesity Res. 2004; 5(4): 253-6. [PMID: 15763939]
- 水谷 伸, 泉 哲郎.
２型糖尿病動物モデル.
医学のあゆみ. 2004; 別冊(4月): 207-10.
- 益山 拓
新しい非肥満２型糖尿病モデルSpontaneously Diabetic Torii (SDT)ラット
岩獣会報 Vol.30,No.4 119-124（2004）
2005
- Masuyama T, Katsuda Y, Shinohara M.
A novel model of obesity-related diabetes: introgression of the Leprfa allele of the Zucker fatty rat into nonobese Spontaneously Diabetic Torii (SDT) rats.
Exp Anim. 2005; 54(1): 13-20. [PMID: 15725677]
- Miao G, Ito T, Uchikoshi F, Tanemura M, Kawamoto K, Shimada K, Nozawa M, Matsuda H.
Beneficial Effects of Pancreas Transplantation: Regeneration of Pancreatic Islets in the Spontaneously Diabetic Torii rat.
Transplant Proc. 2005; 37(1): 226-8. [PMID: 15808602]
- Yamada H, Yamada E, Higuchi A, Matsumura M.
Retinal neovascularisation without ischaemia in the spontaneously diabetic Torii rat.
Diabetologia. 2005; 48(8): 1663-8. [PMID: 15977012]
- 篠原 雅巳, 及川 寿浩, 佐藤 嘉兵.
自然発症糖尿病モデルSDT雌ラットにおける卵巣摘出およびエストロジェン処理が糖尿病病態に及ぼす影響について.
Reprod Immunol Biol. 2005; 20(1): 5-9.
- Miao G, Ito T, Uchikoshi F, Tanemura M, Kawamoto K, Shimada K, Nozawa M, Matsuda H.
Development of islet-like cell clusters after pancreas transplantation in the spontaneously diabetic Torii rat.
Am J Transplant. 2005; 5(10): 2360-7. [PMID: 16162183]
- 山田 耕太郎, 細川 雅也, 藤本 新平, 長嶋 一昭, 福田 一仁, 小川 栄一, 藤田 義人, 上田 直哉, 山田 祐一郎, 稲垣 暢也, 清野 裕.
Spontaneously Diabetic Torii (SDT)ラットにおける糖尿病性下痢の検討.
Diabetes Frontier. 2005; 16(5): 634.
- 益山 拓, 篠原 雅巳, 梯 彰弘.
新しい自然発症２型糖尿病モデルSDTラット.
分子細胞治療. 2005; 4(6): 523-6.
2006
- Matsuoka M, Ogata N, Minamino K, Higuchi A, Matsumura M.
High levels of pigment epithelium-derived factor in the retina of a rat model of type 2 diabetes.
Exp Eye Res. 2006; 82(1):172-8. [PMID: 16054135]
- Sasase T, Ohta T, Ogawa N, Miyajima K, Ito M, Yamamoto H, Morinaga H, Matsushita M.
Preventive effects of glycemic control on ocular complications of Spontaneously Diabetic Torii rat.
Diabetes Obesity Metab. 2006; 8(5): 501-7. [PMID: 16918584]
- 篠原 雅巳, 及川 寿浩, 牛島 太郎, 佐藤 嘉兵.
非肥満2型糖尿病モデル雌性SDTラットにおける卵巣摘出およびエストロジェン処理が糖尿病病態に及ぼす影響について.
Diabetes Frontier. 2006; 17(4): 545-6.
- Kakehashi A, Saito Y, Mori K, Sugi N, Ono R, Yamagami H, Shinohara M, Tamemoto H, Ishikawa SE, Kawakami M, Kanazawa Y.
Characteristics of diabetic retinopathy in SDT rats.
Diabetes Metab Res Rev. 2006; 22(6): 455-61. [PMID: 16572493]
- 鈴木 進.
-2型モデル ②非肥満型モデル- 非肥満糖尿病モデル動物.
Diabetes Frontier. 2006; 17(5): 653-7.
2007
- Yamada K, Hosokawa M, Fujimoto S, Nagashima K, Fukuda K, Fujiwara H, Ogawa E, Fujita Y, Ueda N, Matsuyama F, Yamada Y, Seino Y, Inagaki N.
The spontaneously diabetic Torii rat with gastroenteropathy.
Diabetes Res Clin Pract. 2007; 75(2): 127-34. [PMID: 16959364]
- Ideno J, Mizukami H, Kakehashi A, Saito Y, Okada T, Urabe M, Kume A, Kuroki M, Kawakami M, Ishibashi S, Ozawa K.
Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model.
Int J Mol Med. 2007; 19(1): 75-9. [PMID: 17143550]
- Shinohara M, Masuyama T, Kakehashi A.
The Spontaneously Diabetic Torii (SDT) rat with retinopathy lesions resembling those of humans. Animal Models of Diabetes: Frontiers in Research, Second Edition, ed by Shafir E.
New York, Taylor and Francis Group, 311-321, 2007.
- Sasase T, Morinaga H, Yamamoto H, Ogawa N, Matsui K, Miyajima K, Kawai T, Mera Y, Masuyama T, Shinohara M, Ohta T, Matsushita M.
Increased fat absorption and impaired fat clearance cause postprandial hypertriglyceridemia in Spontaneously Diabetic Torii rat.
Diabetes Res Clin Pract. 2007; 78(1): 8-15. [PMID: 17448560]
- Matsuoka M, Ogata N, Minamino K, Matsumura M.
Leukostasis and pigment epithelium-derived factor in rat models of diabetic retinopathy.
Mol Vis. 2007; 13: 1058-65. [PMID: 17653050]
- Sugiyama T, Okuno T, Fukuhara M, Oku H, Ikeda T, Obayashi H, Ohta M, Fukui M, Hasegawa G, Nakamura N.
Angiotensin II receptor blocker inhibits abnormal accumulation of advanced glycation end products and retinal damage in a rat model of type 2 diabetes.
Exp Eye Res. 2007; 85(3): 406-12. [PMID: 17678894]
- 大川 勝正, 望月 一男, 志田 英士, 鈴木 敏博, 大場 知子, 松本 透, 保苅 義則, 橋詰 昌幸, 横越 英彦.
若齢期の繰り返しストレスが雄性SDTラットの自発運動量などに及ぼす影響.
Diabetes Frontier. 2007; 18(4): 433.
- 篠原 雅巳, 正田 俊之.
雌性SDTラットの糖尿病性眼合併症の病理組織学的特徴.
Diabetes Frontier. 2007; 18(4): 434-5.
- Ohta T, Matsui K, Miyajima K, Sasase T, Masuyama T, Shoda T, Koizumi H, Shinohara M, Matsushita M.
Effect of insulin therapy on renal changes in Spontaneously Diabetic Torii rats.
Exp Anim. 2007; 56: 355-62.
- Shoda T, Shinohara M, Takahashi T, Miyajima K, Kakehashi A, Miyakawa Y.
Histopathological features of diabetic ocular complications in the Spontaneously Diabetic Torii (SDT) Rat.
J Toxicol Pathol. 2007; 20: 179-83.
- Srinivasan K, Ramarao P.
Animal models in type 2 diabetes research: An overview.
Indian J Med Res 125, March 2007, 451-472
2008
- Shimada K, Ito T, Tanemura M, Komoda H, Fumimoto Y, Kawamoto K, Nishida T, Kaneko H, Sawa Y.
Development of β-cells in native pancreas after pancreas allo-transplantation in the Spontaneously Diabetic Torii SDT rat.
J Surg Res. 2008; 145(2): 229-37. [PMID: 17764693]
- Fujii H, Hamada Y, Fukagawa M.
Bone formation in spontaneously diabetic Torii-newly established model of non-obese type 2 diabetes rats.
Bone. 2008; 42: 372-9. [PMID: 18037364]
- Ookawa K, Mochizuki K, Yokogoshi H.
Effect of repeated stress in early childhood on the onset of diabetes mellitus in male Spontaneously Diabetic Torii rats.
J Vet Med Sci. 2008; 70(2): 145-51. [PMID: 18319574]
- Kenichi Matsui, Takeshi Ohta, Tomohiro Oda, Tomohiko Sasase, Nobuhisa Ueda, Katsuhiro Miyajima, Taku Masuyama, Masami Shinohara, Mutsuyoshi Matsushita.
Diabetes-associated complications in spontaneously diabetic torii fatty rats.
Exp Anim. 2008; 57(2): 111-21. [PMID: 18421173]
- Shimada K, Ito T, Miao G, Tanemura M, Komoda H, Fumimoto Y, Kawamoto K, Nishida T, Kaneto H, Sawa Y.
Regeneration of beta cells in the native pancreata after syngeneic and allogeneic pancreas transplantations in spontaneously type 2 diabetic Torii rats.
Transplant Proc. 2008; 40(2): 438-40. [PMID: 18374094]
- Okuno T, Oku H, Sugiyama T, Ikeda T.
Electroretinographic study of spontaneously diabetic Torii rats.
Doc Ophthalmol. 2008; 117: 191-6. [PMID: 18343964]
- Fuse M, Yokoi N, Shinohara M, Masuyama T, Kitazawa R, Kitazawa S, Seino S.
Identification of a major locus for islet inflammation and fibrosis in the spontaneously diabetic Torii rat.
Physiol Genomics. 2008; 35(1): 96-105. [PMID: 18612083]
- Fukumoto M, Takai S, Ishizaki E, Sugiyama T, Oku H, Jin D, Sakaguchi M, Sakonjo H, Ikeda T, Miyazaki M.
Involvement of angiotensin II-dependent vascular endothelial growth factor gene expression via NADPH oxidase in the retina in a type 2 diabetic rat model.
Curr. Eye Res. 2008; 33(10): 885-91 [PMID: 18853323]
- Morinaga H, Yamamoto H, Sakata K, Fukuda S, Ito M, Sasase T, Miyajima K, Ueda N, Ohta T, Matsushita M.
Characterization of hepatic glucose metabolism disorder with the progress of diabetes in male Spontaneously Diabetic Torii rats.
J Vet Med Sci. 2008; 70(11): 1239-45. [PMID: 19057144]
- 佐藤江里, 田村綾女, 丹藤雄介, 須田俊宏, 中村光男, 山岸昌一.
Spontaneously Diabetic Torii (SDT)ラットにおけるセルレイン誘導急性浮腫性膵炎とReceptor for Advanced Glycation Endproducts (RAGE)の発現.
弘前医学. 2008; 59: 110-7.
- 秋元敏雄.
非肥満糖尿病モデル動物.
日本臨牀. 2008; 66巻(増刊号3): 611-5.
- 中村二郎.
糖尿病合併症のモデル動物.
日本臨牀. 2008; 66巻(増刊号3): 623-7.
2009
- Hasegawa G, Fukui M, Hosoda H, Asano M, Harusato I, Tanaka M, Shiraishi E, Senmaru T, Sakabe K, Yamasaki M, Kitawaki J, Fujinami A, Ohta M, Obayashi H, Nakamura N.
Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats.
Eur J Pharmacol. 2009; 605(1-3): 164-9. [PMID: 19171132]
- Jin D, Takai S, Sugiyama T, Hayashi T, Fukumoto M, Oku H, Kitaura Y, Ikeda T, Miyazaki M.
Long-Term Angiotensin II Blockade May Improve Not Only Hyperglycemia but Also Age-Associated Cardiac Fibrosis.
J Pharmacol Sci. 2009; 109(2): 275-84. [PMID: 19202318]
- Hamada Y, Fujii H, Fukagawa M.
Role of oxidative stress in diabetic bone disorder.
Bone. 2009; 45(Suppl.1): S35-8.
- Sasase T, Morinaga H, Abe T, Miyajima K, Ohta T, Shinohara M, Matsushita M, Kakehashi A.
Protein kinase C beta inhibitor prevents diabetic peripheral neuropathy, but not histopathological abnormalities of retina in Spontaneously Diabetic Torii rat.
Diabetes Obes Metab. 2009; 11(11): 1084-7. [PMID: 19614949]
- Matsui K, Oda T, Nishizawa E, Sano R, Yamamoto H, Fukuda S, Sasase T, Miyajima K, Ueda N, Ishii Y, Ohta T, Matsushita M.
Pancreatic Function of Spontaneously Diabetic Torii Rats in Pre-Diabetic Stage.
Exp Anim. 2009; 58(4): 363-74. [PMID: 19654434]
- Inokuchi C, Ueda H, Hamaguchi T, Miyagawa J, Shinohara M, Okamura H, Namba M.
Role of macrophages in the development of pancreatic islet injury in spontaneously diabetic torii rats.
Exp Anim. 2009; 58(4): 383-94. [PMID: 19654436]
- Morinaga H, Ohta T, Matsui K, Sasase T, Fukuda S, Ito M, Ueda M, Ishii Y, Miyajima K, Matsushita M.
Effect of food restriction on adipose tissue in spontaneously diabetic Torii fatty rats.
Exp Diabetes Res. 2009; 2009: Article ID 715057. [PMID: 19696902]
- Matsumoto Y, Torimoto K, Matsuyoshi H, Hirayama A, Fujimoto K, Yoshimura N, Hirao Y.
Long-term effects of diabetes mellitus on voiding function in a new model of type 2 diabetes mellitus, the Spontaneously Diabetic Torii (SDT) rat.
Biomed Res. 2009; 30(6): 331-5. [PMID: 20051641]
2010
- Fukuda M, Nakanishi Y, Fuse M, Yokoi N, Hamada Y, Fukagawa M, Negi A, Nakamura M.
Altered expression of aquaporins 1 and 4 coincides with neurodegenerative events in retinas of spontaneously diabetic Torii rats.
Exp Eye Res. 2010; 90(1): 17-25. [PMID: 19748503]
- Fujii H, Kono K, Nakai K, Goto S, Komaba H, Hamada Y, Shinohara M, Kitazawa R, Kitazawa S, Fukagawa M.
Oxidative and Nitrosative Stress and Progression of Diabetic Nephropathy in Type 2 Diabetes.
Am J Nephrol. 2010; 31(4): 342-52. [PMID: 20224273]
- Sasase T.
Pathophysiological characteristics of diabetic ocular complications in spontaneously diabetic Torii rat.
J Ophthalmol. 2010; 2010: 615641 (7pages). [PMID: 20508774]
- Ishii Y, Ohta T, Sasase T, Morinaga H, Hata T, Miyajima K, Katusda Y, Masuyama T, Shinohara M, Kakutani M, Matsushita M.
A high-fat diet inhibits the progression of diabetes mellitus in type 2 diabetic rats.
Nutr Res. 2010; 30(7): 483-91. [PMID: 20797481]
- Kishi H, Komatsu W, Miura Y, Kawanobe T, Nonaka T, Ohhira S.
Effects of habitual perilla (shiso) tea drinking on the incidence of diabetes mellitus in spontaneously diabetic Trii (SDT)rats.
Biosci Biotechnol Biochem. 2010; 74(12): 2490-3. [PMID: 21150101]
- Ohta T, Miyajima K, Yamada T.
Changes in glycolipid metabolism during a high-sucrose feeding in Spontaneously Diabetic Torii (SDT) rats, a genetic model of nonobese type 2 diabetes. J.
Anim. Vet. Adv. 2010; 9 (22): 2883-2889. [PMID: none]
2011
- Fukuda M, Naka M, Mizokami J, Negi A, Nakamura M.
Diabetes induces expression of aquaporin-0 in the retinal nerve fibers of spontaneously diabetic Torii rats.
Exp Eye Res. 2011; 92(3): 195-201. [PMID: 21232536]
- Masami Shinohara.
Establishment and Clinical Features in Spontaneously Diabetic Torii Rat.
The Open Diabetes J. 2011; 4: 18-20. [PMID: none]
- Norihide Yokoi, Masanori Fuse, Susumu Seino.
Genetics of the Spontaneously Diabetic Torii Rat.
The Open Diabetes J. 2011; 4: 21-5. [PMID: none]
- Taku Masuyama.
Characteristics of Diabetes in the SDT Rat.
The Open Diabetes J. 2011; 4: 26-9. [PMID: none]
- Sumiaki Fukuda, Katsuhiro Miyajima, Tomohiko Sasase, Takeshi Ohta.
Spontaneously Diabetic Torii Lepr fa (SDT Fatty) Rat: A Novel Model of Obese Type 2 Diabetes.
The Open Diabetes J. 2011; 4: 30-6. [PMID: none]
- Akihiro Kakehashi.
Diabetic Ocular Complications in the SDT Rat.
The Open Diabetes J. 2011; 4: 37-40. [PMID: none]
- Fumihiko Toyoda, Akihiro Kakehashi, Kana Hashimoto, Nozomi Kinoshita, Chiho Kanbara, Hiroko Yamagami, Hiroyuki Tamemoto, San-e Ishikawa, Yoh Dobashi, Masanobu Kawakami, Yasunori Kanazawa.
Accumulation of AGEs and VEGF in Eyes of SDT Rats.
The Open Diabetes J. 2011; 4: 41-4. [PMID: none]
- Takeshi Ohta, Tomohiko Sasase.
Diabetic Nephropathy in Spontaneously Diabetic Torii (SDT) Rats.
The Open Diabetes J. 2011; 4: 45-9. [PMID: none]
- Tomohiko Sasase, Takeshi Ohta.
Torii Rat.
The Open Diabetes J. 2011; 4: 50-4. [PMID: none]
- Yasuko Mera, Hisayo Morinaga, Takeshi Ohta, Tomohiko Sasase.
Glucose and Lipid Metabolism in Spontaneously Diabetic Torii Rat.
The Open Diabetes J. 2011; 4: 55-9. [PMID: none]
- Masami Shinohara, Toshihiro Oikawa, Kahei Sato, Yasunori Kanazawa.
Effect of Oophorectomy and Estrogen Administration on Diabetic Pathogenesis in Female Spontaneously Diabetic Torii Rats.
The Open Diabetes J. 2011; 4: 96-100. [PMID: none]
- Akihiro Kakehashi, Mikiko Takezawa, Fumihiko Toyoda, Nozomi Kinoshita, Chiho Kambara, Hiroko Yamagami, Noriaki Kato, San-e Ishikawa, Masanobu Kawakami, Yasunori Kanazawa.
Aldose Reductase Inhibitor Fidarestat Prevents Diabetic Ocular Complications in Spontaneously Diabetic Torii Rats.
The Open Diabetes J. 2011; 4: 101-7. [PMID: none]
- Fumihiko Toyoda, Akihiro Kakehashi, Ayumi Ota, Nozomi Kinoshita, Chiho Kambara, Hiroko Yamagami, Hiroyuki Tamemoto, Hiroto Ueba, Yoh Dobashi, San-e Ishikawa, Masanobu Kawakami, Yasunori Kanazawa.
Prevention of Proliferative Diabetic Retinopathy and Cataract in SDT Rats with Aminoguanidine, an Anti-Advanced Glycation End Product Agent.
The Open Diabetes J. 2011; 4: 108-13. [PMID: none]
- Nozomi Kinoshita, Akihiro Kakehashi, Yoh Dobashi, Ryuichiro Ono, Fumihiko Toyoda, Chiho Kambara, Hiroko Yamagami, Yusuke Kitazume, Eiji Kobayashi, Yasuhiro Osakabe, Motoshige Kudo, Masanobu Kawakami, Yasunori Kanazawa.
Effects of Topical Nipradilol on Early Diabetic Retinopathy in SDT Rats.
The Open Diabetes J. 2011; 4: 114-8. [PMID: none]
- Hiroaki Mizukami, Masashi Urabe, Akihiro Kume, Keiya Ozawa.
Gene Therapy for Diabetic Retinopathy in Animal Models and Humans.
The Open Diabetes J. 2011; 4: 119-22. [PMID: none]
- Takeshi Ohta, Katsuhiro Miyajima, Takahisa Yamada.
Pathophysiological Changes in Pre-Diabetic Stage of Spontaneously Diabetic Torii (SDT) Rats.
J Anim Vet Adv. 2011; 10(7): 813-7. [PMID: none]
- Goto S, Fujii H, Kono K, Nakai K, Hamada Y, Yamato H, Shinohara M, Kitazawa R, Kitazawa S, Nishi S, Fukagawa M.
Carvedilol ameliorates low-turnover bone disease in non-obese type 2 diabetes.
Am J Nephrol. 2011; 34(3): 281-90. [PMID: 21829007]
2012
- Masuda T, Muto S, Fujisawa G, Iwazu Y, Kimura M, Kobayashi T, Nonaka-Sarukawa M, Sasaki N, Watanabe Y, Shinohara M, Murakami T, Shimada K, Kobayashi E, Kusano E.
Heart angiotensin II-induced cardiomyocyte hypertrophy suppresses coronary angiogenesis and progresses diabetic cardiomyopathy.
Am J Physiol Heart Circ Physiol. 2012; 302(9): H1871-83. [PMID: 22389386]
- Mifune T, Nishi Y, Tajiri Y, Masuyama T, Hosoda H, Kanagawa K, Kojima M.
Increased production of active ghrelin is relevant to hyperphagia in nonobese spontaneously diabetic Torii rats.
Metabolism. 2012; 61: 491-5. [PMID: 22001335]
- Ohta T, Shinohara M, Yamamoto T, Yamada T.
Pancreatic abnormalities at a young age in Spontaneously Diabetic Torii (SDT) rats.
J Anim Vet Adv. 2012; 11(9): 1322-1326.
- Ohta T, Miyajima K, Shinohara M, Yamamoto T, Yamada T.
Inhibition of postprandial hyperglycemia prevents the incidence of diabetes in Spontaneously Diabetic Torii (SDT) rats.
J Anim Vet Adv. 2012; 11(10): 1583-7.
- Ohta T, Morinaga H, Yamamoto T, Yamada T.
Effect of phlorizin on metabolic abnormalities in Spontaneously Diabetic Torii (SDT) rats.
Open Journal of Animal Sciences. 2012; 2(2): 113-8.
- 篠原雅巳.
"SDTラット". 疾患モデルの作製と利用―糖尿病・肥満/感染症.
エル・アイ・シー, 2012, p.65-78.
- Kim J, Shon E, Kim CS, Kim JS.
Renal podocyte injury in a rat model of type 2 diabetes is prevented by metformin.
Exp Diabetes Res. 2012; 2012: 210821. [PMID: 23056035]
- Inubushi T, Kamemura N, Oda M, Sakurai J, Nakaya Y, Harada N, Suenaga M, Matsunaga Y, Ishidoh K, Katunuma N.
L-tryptophan suppresses rise in blood glucose and preserves insulin secretion in type-2 diabetes mellitus rats.
J Nutr Sci Vitaminol (Tokyo). 2012; 58(6): 415-22. [PMID: 23419400]
- Yamaguchi T, Ohta T, Morinaga H, Hata T, Sato E, Matsushita M.
Changes in protein tyrosine phosphatase activity in Spontaneously Diabetic Torii (SDT) rats.
Open J. Anim. Sci. 2012; 2(4): 253-257.
- Lakshmanan A.P, Harima M, Sukumaran V, Soetikno V, R A Thandavarayan, Suzuki K, Kodama M, Nagata M, Takagi R, Watanabe K.
Modulation of AT-1R/AMPK-MAPK cascade plays crucial role for the pathogenesis of diabetic cardiomyopathy in transgenic type 2 diabetic(Spontaneous Diabetic Torii)rats.
Bioch. Pharm. 83(2012) 653-660
- Robinson R, Barathi V A, Chaurasia S S, Wong T Y, Kern T S.
Update in animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals.
Disease Models & Mechan. 5, 444-456(2012)
- Hirata M, Serizawa K, Aizawa K, Yogo K, Tashiro Y, Takeda S, Moriguchi Y, Endo K, Fukagawa M.
22-Oxacalcitriol prevents progress of endothelial dysfunction through antioxidative effects in rats with type 2 diabetes and early-stage nephropathy.
Nephrol. Dial. Transplant 2012, 1-8.
- 平尾直啓、龍門徳彦、稲葉信博、千葉薫、笹瀬智彦、太田勲毅
SDT-fa/faおよびSDT-+/+ラットの糖尿病発症・進展に2種の基礎飼料が及ぼす影響
実験動物技術 第47巻2号 3-11（2012）
- Kim CS, Kim J, Kim YS, Jo K, Lee YM, Jung DH, Lee IS, Kim JH, Kim JS.
Improvement in Diabetic Retinopathy through Protection against Retinal Apoptosis in Spontaneously Diabetic Torii Rats Mediated by Ethanol Extract of Osteomeles schwerinae C.K. Schneid.
Nutrients. 2019 Mar 4; 11(3). [PMID: 30836664]
- Maejima T, Kumagai K, Yabe K, Yasuno K, Ishikawa K, Okado K, Sasaki N, Kai K, Mori K.
Urothelial hyperplasia with calculi (papillomatosis) in the urinary bladder of a male spontaneous diabetic Torii rat.
Journal of Toxicologic Pathology, August 31, 2019 [PMID: none]
- Tanaka Y, Takagi R, Ohta T, Sasase T, Kobayashi M, Toyoda F, Shimmura M, Kinoshita N, Takano H, Kakehashi A.
Pathological Features of Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats.
J Diabetes Res. 2019 Sep 15; 2019: 8724818. [PMID: 31637263]
2013
- Kono K, Fujii H, Nakai K, Goto S, Kitazawa R, Kitazawa S, Shinohara M, Hirata M, Fukagawa M, Nishi S.
Anti-oxidative effect of vitamin D analog on incipient vascular lesion in non-obese type 2 diabetic rats.
Am J Nephrol. 2013; 37(2): 167-74. [PMID: 23406697]
- Tomohiko Sasase, Takeshi Ohta, Taku Masuyama, Norihide Yokoi, Akihiro Kakehashi, Masami Shinohara.
The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications.
Journal of Diabetes Research. Volume 2013, Article ID 976209, 12 pages.
- Ota A, Kakehashi A, Toyoda F, Kinoshita N, Shinmura M, Takano H, Obata H, Matsumoto T, Tsuji J, Dobashi Y, Fujimoto WY, Kawakami M, Kanazawa Y.
Effects of long-term treatment with ranirestat, a potent aldose reductase inhibitor, on diabetic cataract and neuropathy in spontaneously diabetic torii rat.
J Diabetes Res. 2013; 2013: 175901. [PMID: 23671855]
- Nakai K, Fujii H, Kono K, Goto S, Kitazawa R, Kitazawa S, Hirata M, Shinohara M, Fukagawa M, Nishi S.
Vitamin D Activates the Nrf2-Keap1 Antioxidant Pathway and Ameliorates Nephropathy in Diabetic Rats.
Am J Hypertens. 2013 Sep 11. [PMID: 24025724]
- Sasase T, Ohta T, Masuyama T, Yokoi N, Kakehashi A, Shinohara M.
The Spontaneously Diabetic Torii (SDT) rat: An animal model of non-obese type 2 diabetes with severe diabetic complications.
Exp. Diabetes Res. 2013; 2013: 976209. [PMID: 23691526]
- 住川守男、龍門徳彦、稲葉信博、榊原和佳子、前野孝之、千葉薫、石井幸仁、木村修一、美谷島克宏、太田毅.
SDTラットにおける卵巣摘出による生理学的変化の検討.
実験動物技術. 2013; 48(1): 3-8.
- 榊原和佳子、龍門徳彦、住川守男、稲葉信博、前野孝之、千葉薫、石井幸仁、木村修一、Ton Bing、太田毅、山田宜永.
Spontaneously Diabetic Torii (SDT)ラットの糖、脂質および骨代謝に精巣摘出が及ぼす影響.
実験動物技術. 2013; 48(2): 79-85.
2014
- Mukai E, Ohta T, Kawamura H, Lee E-Y, Morita A, Sasase T, Miyajima K, Inagaki N, Iwanaga T, Miki T.
Enhanced vascular endothelial growth factor signaling in islets contributes to βcell injury and consequential diabetes in Spontaneously Diabetic Torii rats.
Diabetes Res. Clin. Pract. 2014; 106: 303-311. [PMID: 25262109]
- Toyoda F, Tanaka Y, Ota A, Shimmura M, Kinoshita N, Takano H, Matsumoto T, Tsuji J, Kakehashi A.
Effect of ranirestat, a new aldose reductase inhibitor, on diabetic retinopathy in SDT rats.
J Diabetes Res. 2014; 2014: 672590. [PMID: 25215304]
- Nakai K, Fujii H, Kono K, Goto S, Kitazawa R, Kitazawa S, Hirata M, Shinohara M, Fukagawa M, Nishi S.
Vitamin D activates the Nrf2-Keap1 antioxidant pathway and ameliorates nephropathy in diabetic rats.
Am J Hypertens. 2014 Apr; 27(4): 586-95. [PMID: 24025724]
2015
- Goto S, Fujii H, Kono K, Nakai K, Awata R, Yonekura Y, Hirata M, Shinohara M, Nishi S, Fukagawa M.
22-Oxacalcitriol attenuates bone loss in nonobese type 2 diabetes.
Bone. 2015 May; 74: 153-9. [PMID: 25645030]
- Yokoi N, Beppu M, Yoshida E, Hoshikawa R, Hidaka S, Matsubara T, Shinohara M, Irino Y, Hatano N, Seino S.
Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.
Metabolomics. 2015; 11(5): 1277-1286. [PMID: 26366137]
- Sasase T, Yokoi N, Pezzolesi MG, Shinohara M.
Animal models of diabetes and metabolic disease 2014.
J Diabetes Res. 2015; 2015: 571809. [PMID: 25973428]
- Yonekura Y, Fujii H, Nakai K, Kono K, Goto S, Shinohara M, Nishi S.
Anti-oxidative Effect of the β-blocker Carvedilol on Diabetic Nephropathy in Non-obese Type 2 Diabetic Rats.
Clin Exp Pharmacol Physiol. 2015 Jul 14. doi: 10.1111/1440-1681.12447. [PMID: 26173411]
- Chen SJ, Aikawa C, Yoshida R, Matsui T.
Methylglyoxal-derived hydroimidazolone residue of plasma protein can behave as a predictor of prediabetes in Spontaneously Diabetic Torii rats.
Physiol Rep. 2015 Aug; 3(8). [PMID: 26265747]
- Toyoda F, Tanaka Y, Shimmura M, Kinoshita N, Takano H, Kakehashi A.
Diabetic Retinal and Choroidal Edema in SDT Rats.
J Diabetes Res. 2016; 2016: 2345141. [PMID: 26783535]
- Kato T, Relator R, Ngouv H, Hirohashi Y, Takaki O, Kakimoto T, Okada K.
Segmental HOG: new descriptor for glomerulus detection in kidney microscopy image.
BMC Bioinformatics. 2015 Sep 30; 16: 316. [PMID: 26423821]
- Fujii H, Nakai K, Yonekura Y, Kono K, Goto S, Hirata M, Shinohara M, Nishi S, Fukagawa M.
The Vitamin D Receptor Activator Maxacalcitol Provides Cardioprotective Effects in Diabetes Mellitus.
Cardiovasc Drugs Ther. 2015 Nov 25. [PMID: 26602563]
- Takaoka K, Yamamura M, Nishioka T, Abe T, Tamaoka J, Segawa E, Shinohara M, Ueda H, Kishimoto H, Urade M.
Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats.
PLoS One. 2015 Dec 14; 10(12): e0144355. [PMID: 26659123]
- 前野孝之、榊原和佳子、住川守男、平尾直啓、山中沙織、千葉薫、勝田佳朋、槇美実、剣持佑介、Ton Bing、山田宜永、太田毅、美谷島克宏.
Spontaneously Diabetic Torii (SDT)ラットにおける片腎摘出術の有用性の検討.
実験動物技術. 2015; 50(1): 3-10.
- Yokoi N.
Elucidation of genetic factors in diabetes based on studies of animal models.
Diabetology International December 2015, Volume 6, Issue 4, pp 255-260 [PMID: none]
2016
- 稲葉信博、剣持佑介、龍門徳彦、平尾直啓、山中沙織、千葉薫、太田毅、山田宜永、美谷島克宏.
非肥満2型糖尿病モデル雄性SDTラットの精子形成における病態生理学的変化.
北信越畜産学会報、112号、1-7頁 2016
- Karthikeyan M.
Balasubramanian T and Pawan K. In-vivo Animal Models and In-vitro Techniques for Screening Antidiabetic Activity
J Develop Drugs 5:153 [PMID: none]
- Toyoda F, Tanaka Y, Shimmura M, Kinoshita N, Takano H, Kakehashi A.
Diabetic Retinal and Choroidal Edema in SDT Rats.
J Diabetes Res. 2016; 2016: ArticleID 2345141. [PMID: 26783535]
2017
- Ohta T, Toriniwa Y, Ryumon N, Inaba N, Hirao T, Yamanaka S, Maeno T, Sakakibara W, Sumikawa M, Chiba K, Nakamura A, Miyajima K, Fatchiyah F, Yamada T.
Maternal high-fat diet promotes onset of diabetes in rat offspring.
Anim Sci J. 2017 Jan; 88(1): 149-155. [PMID: 27145882]
- Taniai-Riya E, Miyajima K, Kakimoto K, Ohta T, Yasui Y, Kemmochi Y, Anagawa-Nakamura A, Toyoda K, Takahashi A, Shoda T.
Hepatocellular adenoma with severe fatty change in a male Spontaneously Diabetic Torii rat.
J Toxicol Pathol. 2017; 30: 69–73. [PMID: 28190927]
- Serizawa K, Yogo K, Tashiro Y, Kawasaki R, Endo K, Shimonaka Y, Hirata M.
Epoetin beta pegol ameliorates flow‐mediated dilation with improving endothelial nitric oxide synthase coupling state in nonobese diabetic rats
Cardiovasc Ther. 2017 Apr; 35(2): e12250. [PMID: 28054454]
- Chen SJ, Aikawa C, Yoshida R, Kawaguchi T, Matsui T.
Anti-prediabetic effect of rose hip (Rosa canina) extract in spontaneously diabetic Torii rats.
J Sci Food Agric. 2017 Feb 9. [PMID: 28182280]
- Watanabe K, Fujii H, Goto S, Nakai K, Kono K, Watanabe S, Shinohara M, Nishi S.
Newly Developed Rat Model of Chronic Kidney Disease-Mineral Bone Disorder.
J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. [PMID: 28674323]
- Gonzalo Miyagusuku-Cruzado, Naoki Morishita, Keiichi Fukui, Norihiko Terahara, Toshiro Matsui.
Anti-Prediabetic Effect of 6-O-Caffeoylsophorose in Prediabetic Rats and Its Stimulation of Glucose Uptake in L6 Myotubes.
Food Science and Technology Research. 2017; 23(3): 449-456.
- Kim J, Jo K, Kim CS, Kim JS.
Aster koraiensis extract prevents diabetes-induced retinal vascular dysfunction in spontaneously diabetic Torii rats.
BMC Complement Altern Med. 2017 Nov 23; 17(1): 497. [PMID: 29169356]
- 横田 淳司
糖尿病に合併する腱障害の病態 －自然発症2型糖尿病モデルラットの腱でのペントシジンの蓄積と終末糖化産物受容体の発現の検討－
日本臨床整形外科学会雑誌 43(1), 17-24, 2017
- Cammalleri M, Del Monte M, Locri F, Marsili S, Lista L, De Rosa M, Pavone V, Rusciano D, Bagnoli P.
Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System.
J Diabetes Res. 2017; Article ID 2904150, 1-18
2018
- Masuda T, Watanabe Y, Fukuda K, Watanabe M, Onishi A, Ohara K, Imai T, Koepsell H, Muto S, Vallon V, Nagata D.
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat.
Am J Physiol Renal Physiol. 2018 Sep 1; 315(3): F653-F664. [PMID: 29790389]
- Watanabe K, Fujii H, Goto S, Nakai K, Kono K, Watanabe S, Shinohara M, Nishi S.
Newly Developed Rat Model of Chronic Kidney Disease-Mineral Bone Disorder.
J Atheroscler Thromb. 2018 Feb 1; 25(2): 170-177. [PMID: 28674323]
- Sohn E, Kim J, Kim CS, Jo K, Kim JS.
Osteomeles schwerinae Extract Prevents Diabetes-Induced Renal Injury in Spontaneously Diabetic Torii Rats.
Evid Based Complement Alternat Med. 2018 Apr 24; 2018: 6824215.
- Ohta T, Yamada T, Kamiya T, Gotoh T, Tsubaki M, Shinohara M.
Quick-fat diet inhibits the development of diabetes in Spontaneously Diabetic Torii rats.
Thai Journal of Pharmaceutical Sciences. 2018; 42(4): 183-187 [PMID: none]
- Ohta T, Sasase T, Gotoh T, Shinohara M, Sirichaiyakul P, Furuta S, Techasakulsin R, Kamiya T, Yoshida C, Yamada T.
Non-Obese Type 2 diabetic Rat Models-GK Rat and SDT Rat.
Open J. Anim. Sci. 2018; (8): 396-420
2019
- Kim CS, Kim J, Kim YS, Jo K, Lee YM, Jung DH, Lee IS, Kim JH, Kim JS.
Improvement in Diabetic Retinopathy through Protection against Retinal Apoptosis in Spontaneously Diabetic Torii Rats Mediated by Ethanol Extract of Osteomeles schwerinae C.K. Schneid.
Nutrients. 2019 Mar 4; 11(3). [PMID: 30836664]
- Maejima T, Kumagai K, Yabe K, Yasuno K, Ishikawa K, Okado K, Sasaki N, Kai K, Mori K.
Urothelial hyperplasia with calculi (papillomatosis) in the urinary bladder of a male spontaneous diabetic Torii rat.
Journal of Toxicologic Pathology, August 31, 2019 [PMID: none]
- Tanaka Y, Takagi R, Ohta T, Sasase T, Kobayashi M, Toyoda F, Shimmura M, Kinoshita N, Takano H, Kakehashi A.
Pathological Features of Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats.
J Diabetes Res. 2019 Sep 15; 2019: 8724818. [PMID: 31637263]
2020
- Kazuma Kondo, Naohito Yamada, Yusuke Suzuki, Tatsuji Hashimoto, Kaoru Toyoda, Tadakazu Takahashi, Akio Kobayashi, Shoichiro Sugai, Kouichi Yoshinari.
Enhancement of acetaminophen-induced chronic hepatotoxicity in spontaneously diabetic torii (SDT) rats.
J Toxicol Sci. 2020; 45(5): 245-260. [PMID: 32404557]
- Yoshitomi Nakane, Yusuke Kemmochi, Naoto Ogawa, Tomohiko Sasase, Takeshi Ohta, Yoshikazu Higami, Fumio Fukai.
Hyperglycemia contributes to the development of Leydig cell hyperplasia in male Spontaneously Diabetic Torii rats.
J Toxicol Pathol. 2020 Apr; 33(2): 121-129. [PMID: 32425345]
2021
- Kazuma Kobayashi, Tomohiko Sasase, Yukihito Ishii, Yoshiaki Katsuda, Katsuhiro Miyajima, Takahisa Yamada, Takeshi Ohta.
The sphingosine-1-phosphate receptor modulator, FTY720, prevents the incidence of diabetes in Spontaneously Diabetic Torii rats.
Clin Exp Pharmacol Physiol. 2021 Jun; 48(6): 869-876. [PMID: 32920892]
- Tatsuya Maekawa, Sanae Nakamura, Katsuhiro Miyajima, Kinuko Uno, Ayane Yamaguchi, Kouhei Mandai, Takayuki Gotoh, Masami Shinohara, Yuichi Shinozaki, Tomohiko Sasase, Fatchiyah Fatchiyah, Takeshi Ohta.
Ocular Changes –Cataract And Retinal Lesion- In Spontaneously Diabetic Torii (SDT) Fatty Rats, An Obese Type 2 Diabetic Model.
Journal of Smart Bioprospecting and Technology. 2021; 2(2): 81-86.
2022
- Tetsuya Hasegawa, Rina Takagi, Yoshiaki Tanaka, Takeshi Ohta, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Shin-Ichi Muramatsu, Toshikatsu Kaburaki, Akihiro Kakehashi.
Differences in the Effects of Pentobarbital Anesthetic and Combination of Medetomidine Hydrochloride, Midazolam, and Butorphanol Tartrate Anesthetic on Electroretinogram in Spontaneously Diabetic Torii Fatty Rats
Biomed Hub. 2022 Sep 9; 7(3): 106-114. [PMID: 36262406]
FAQ
- Q: What is included on this page?
- A: This page provides an academic reference list for SDT/Jcl, along with a related product section and an inquiry link.
Q: How are the references organized?- A: References are presented in the original "References by Year" list. You can jump to each year using the year index on this page.
Q: Can I browse the same references by research purpose?- A: Yes. The topic-based sections above provide a research-purpose view that points to selected publications listed in the year-based archive.
Q: Which years are available in the References by Year index?- A: The year index on this page includes 2000 through 2022.
Q: Where can I find the related product information for SDT/Jcl?- A: The related product information is provided in the "Related CLEA Japan product: SDT/Jcl" section on this page.
Q: How can I contact CLEA Japan about this model?- A: The "Inquiry" section on this page includes a link to the contact form for questions about SDT/Jcl.
