Dapagliflozin Alone or Combined with Ramipril Improves Hyperglycemia, Hypertension, and Prevents Kidney Complications and GFR Decline in the Nephrectomized SDT Fatty Rat Model of Diabetic Nephropathy.

Key Word:
Dapagliflozin（ダパグリフロジン）、Ramipril（ラミプリル）、GFR（クレアチニンクリアランス）、Hyperglycemia（高血糖）、Hypertension（高血圧） obese, type 2 diabetic model（肥満、2型糖尿病モデル）

François Briand¹, Masami Shinohara², Emmanuel Brousseau¹, Takeshi Ohta³, Yasushi Kageyama², Thierry Sulpice¹

¹Physiogenex, Labège, France; ²CLEA Japan Inc. Meguro-ku, Tokyo, Japan, ³Central Pharmaceutical Research Institute, Japan Tobacco Inc., Osaka, Japan

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• ISN Frontier Meetings 2018: Keio Plaza Hotel Tokyo in Shinjyuku, Tokyo, Japan. / 京王プラザホテル（東京都、新宿）
• October 31 - November 1, 2017

Related CLEA Japan product: SDT fatty/Jcl

For the animal model, please click here ▼

 https://www.clea-japan.com/en/products/diabetes/item_a0150

 https://www.clea-japan.com/products/diabetes/item_a0150

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