C3H/HeJJcl
C3H/HeNJcl
Animals/Inbred Strains/
Ordering name: C3H/HeJJcl
C3H/HeNJcl
Nomenclature: C3H/HeJJcl, C3H/HeNJcl
Availability: Live colony
Characteristics
Coat color: Agouti. Known as a poly-tumor strain, it is primarily used for cancer, immunology, and radiation biology research. C3H/HeJ is resistant to endotoxin, while C3H/HeN is susceptible (Karasawa et al., 1990).
Coat color gene: AA BB CC (agouti)
Use
Used in cancer, immunology, radiation biology, and hair growth research.
Background data(Body weight, hematology, blood chemistry, organ weight)
◆ C3H/HeNJcl mice: 10-week data(*Japanese)
◆ C3H/HeJJcl mice: 10-week data(*Japanese)
Origin
1920: Dr. Strong crossed Bagg's albino female mice (later BALB) with dba male mice (later DBA), and the group with a high incidence of
mammary cancer was named C3H. The group with a low incidence was named CBA.
1941: The strain was transferred to Dr. Heston and became C3H/He.
1947: It was introduced to the Jackson Laboratory from Dr. Heston and supplied as C3H/HeJ.
1977: C3H/HeN (F=124) was introduced to the National Institute of Health from NIH and CLEA Japan began production and supply as
C3H/HeNJcl from 1979.
1986: C3H/HeJ (F=187) was introduced to our company from the Jackson Laboratory, and we began production and supply as C3H/HeJJcl.
Our Contract Research Services related with This Animal
For details on our contract research services, including cryopreserved embryos, contracted testing, and the provision of research materials such as blood and organs, please click here .