Microbiological Cleaning
Services//
Microbiological Cleanning
CLEA Japan can create SPF (CLEA standard) animals or germ free animals from customer-supplied animals or frozen embryos. We prepare from a basic size, use small vinyl isolator (VI) with 4 pairs, to large order like a cleaning service for the production colony establishment.
- We make frozen embryos from customer-supplied animals.
- The frozen embryos are melted and transplanted to the recipient animals. After that, cesarean section is executed and the uterus is removed.
- The fetus is removed at a surgical VI and nursed by foster animal inside small VI or large VI.
- After weaning, the microbiological test is executed to the fetus to confirm CLEA standard SPF or germ free condition.
- We can deliver the frozen embryos or sperm, too.
- Please supply 3 free fertile male animals by 1 strain.
- We collect 100 to 150 embryos per 1 strain for this egg collecting service.
- We return the surplus embryos after the service.
- We transplant embryos to 3 recipient animals and deliver 18 offsprings for 1 strain.
- Microbiological monitoring is executed by Central Institute for Experimental Medicine and Life Science (CIEM), ICLAS monitoring center.
* We estimate the microbiological monitoring for immunodeficiency animals in a different manner. Please ask.
Rederivation from a frozen embryo
- We prepare the number of animals as your study needs.
- We can execute this microbiological cleaning service with frozen embryo creating service together.
- You can specify genotype, week of age, and/or etc. for the cleaned animals to deliver.
For Questions and Inquiry
- Please contact to CLEA Japan
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- Our sales representatives will contact you to do hearing the details.