TNP-IgE/Jcl

Animals/Genetically Modified Animals/

TNP-IgE/Jcl

Ordering name: TNP-IgE/Jcl
Nomenclature: BALB/cA-Tg(IgE-Hb4)Rin Tg(IgE-kLb4)Rin/Jcl
Availability: Cryopreserved
Genetically modified animal (subject to the Cartagena Protocol on Biosafety)

Characteristics

OVA-IgE and TNP-IgE mice are genetically modification BALB/c mice constantly creating IgE at the egg albumin (OVA) and hapten TNP (Trinitrophenol), used as allergen frequently. This model can show both acute and chronic allergy reactions with quit high productivity by allergen administration without immunitas.
1. Unnecessary percutaneous immunization
2. High reproductively of allergy reaction
3. Clear study result due to the simple phenotype strain

Detailed Catalog (PDF)

Some of the materials in the PDF document are excerpted here.

▼ Stable production of allergen-specific IgEStable production of allergen-specific Ig

▼ Induction of systemic anaphylaxisInduction of systemic anaphylaxis

   ▼ For more details(*Japanese) ▼nod pdf thumbnail

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◆References(*Japanese)
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Our Contract Research Services related with This Animal 

For details on our contract research services, including cryopreserved embryos, contracted testing, and the provision of research materials such as blood and organs, please click here .

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