Animals/Genetically Modified Animals/
Ordering name: TNP-IgE/Jcl
Nomenclature: BALB/cA-Tg(IgE-Hb4)Rin Tg(IgE-kLb4)Rin/Jcl
Availability: Cryopreserved
Genetically modified animal (subject to the Cartagena Protocol on Biosafety)
OVA-IgE and TNP-IgE mice are genetically modification BALB/c mice constantly creating IgE at the egg albumin (OVA) and hapten TNP (Trinitrophenol), used as allergen frequently. This model can show both acute and chronic allergy reactions with quit high productivity by allergen administration without immunitas.
1. Unnecessary percutaneous immunization
2. High reproductively of allergy reaction
3. Clear study result due to the simple phenotype strain
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